Evidence map›Paper›PMID 32875123›Full record

ArticleJournal of clinical tuberculosis and other mycobacterial diseases2020

Tuberculosis preventive therapy (TPT) to prevent tuberculosis co-infection among adults with HIV-associated cryptococcal meningitis: A clinician's perspective.

John Kasibante, Morris K Rutakingirwa, Enock Kagimu, Kenneth Ssebambulidde, Jayne Ellis, Lillian Tugume, Edward Mpoza, Fiona Cresswell, David B Meya

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical tuberculosis and other mycobacterial diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

John KasibanteInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Morris K RutakingirwaInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Enock KagimuInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Kenneth SsebambuliddeInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Jayne EllisInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Lillian TugumeInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Edward MpozaInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Fiona CresswellClinical Research Department, London School of Hygiene & Tropical Medicine, Keppel St, Bloomsbury, London WC1E 7HT, UK.
David B MeyaInfectious Diseases Institute, Makerere University, Kampala, Uganda.
Infectious Diseases Institute · UGMakerere University · UGLondon School of Hygiene & Tropical Medicine · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As part of the END TB strategy, the World Health organization (WHO) recommends provision of tuberculosis preventive therapy (TPT) to all people at high risk of developing active TB disease. Patients with HIV-associated cryptococcal meningitis are severely immunocompromised and therefore should be eligible for TPT. In this commentary we discuss the challenges associated with starting tuberculosis preventive therapy in patients with HIV associated cryptococcal meningitis in a clinical setting, we highlight the benefit, existing gaps and research opportunities of tuberculosis preventive therapy in this patient population.

Indexed as

AIDSCryptococcal meningitisCryptococcosisHIVTuberculosisTuberculosis preventive therapy

Identifiers

PMID32875123
PMCPMC7452161
OpenAlexW3049324493

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.