Evidence map›Paper›PMID 32875080›Full record

ArticleACS central science2020

Engineering Plant Synthetic Pathways for the Biosynthesis of Novel Antifungals.

Amy Calgaro-Kozina, Khanh M Vuu, Jay D Keasling, Dominique Loqué, Elizabeth S Sattely, Patrick M Shih

Abstract read
In one paragraph

Article in ACS central science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. EngineeringACS synthetic biology · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amy Calgaro-KozinaDepartment of Chemical Engineering, Stanford University, Stanford, California 94305, United States.
Khanh M VuuJoint BioEnergy Institute, Emeryville, California 94608, United States.
Jay D KeaslingDepartment of Chemical and Biomolecular Engineering, UC Berkeley, Berkeley, California 94720, United States.
Dominique LoquéJoint BioEnergy Institute, Emeryville, California 94608, United States.
Elizabeth S SattelyDepartment of Chemical Engineering, Stanford University, Stanford, California 94305, United States.
Patrick M ShihJoint BioEnergy Institute, Emeryville, California 94608, United States.

Funding

Discovery and Engineering of Plant Natural Product PathwaysR01GM121527 · NIGMS · STANFORD UNIVERSITY · PI SATTELY, ELIZABETH SUSAN · 2017 to 2025
$2.3M
NIGMS NIH HHS R01 GM121527
6 · The paper itself

Abstract

Plants produce a wealth of biologically active compounds, many of which are used to defend themselves from various pests and pathogens. We explore the possibility of expanding upon the natural chemical diversity of plants and create molecules that have enhanced properties, by engineering metabolic pathways new to nature. We rationally broaden the set of primary metabolites that can be utilized by the core biosynthetic pathway of the natural biopesticide, brassinin, producing

Identifiers

PMID32875080
PMCPMC7453567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.