ReviewWorld journal of clinical oncology2020
Lingual lymph nodes: Anatomy, clinical considerations, and oncological significance.
Review in World journal of clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Case Report: A diagnostic pitfall of diffuse large B-cell lymphoma with hemophagocytic lymphohistiocytosis and atypical tongue pain: the critical role of PET/CT-guided repeat bone marrow biopsy.Frontiers in oncology · 2026Article
- Lymph nodes in oral squamous cell carcinoma: a comprehensive anatomical perspective.Clinical & experimental metastasis · 2024Review
- Prognostic Value of Anteroposterior Extension in Oral Tongue and Floor Squamous Cell Carcinoma.JAMA otolaryngology-- head & neck surgery · 2024Article
- A novel near-infrared EGFR targeting probe for metastatic lymph node imaging in preclinical mouse models.Journal of nanobiotechnology · 2023Article
- Physiology of the tongue with emphasis on taste transduction.Physiological reviews · 2023Review
- Surgical anatomy of the lingual lymph nodes: systematic literature analysis and proposition for topographic classification.Surgical and radiologic anatomy : SRA · 2023Review
- The Role of Peritumoral Depapillation and Its Impact on Narrow-Band Imaging in Oral Tongue Squamous Cell Carcinoma.Cancers · 2023Article
- A novel definition and treatment of hyperinflammation in COVID-19 based on purinergic signalling.Purinergic signalling · 2022Review
- Application of near-infrared fluorescence imaging in lingual lymph node screening and drainage pattern observation for tongue cancer.Frontiers in cell and developmental biology · 2022Article
- A Missing Voice: The Lingual Complex and Osteopathic Manual Medicine in the Context of Five Osteopathic Models.Cureus · 2021Review
- Metastasis to the lateral lingual lymph node located behind the submandibular gland: A case of squamous cell carcinoma of the tongue.Clinical case reports · 2021Article
- Survival Impact of Lingual Lymph Node Metastases in Tongue Cancer: An Analysis Regarding Anatomical Subsites.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lingual lymph nodes are an inconstant group of in-transit nodes, which are located on the route of lymph drainage from the tongue mucosa to the regional nodes in neck levels I and II. There is growing academic data on the metastatic spread of oral cancer, particularly regarding the spreading of oral tongue squamous cell carcinoma to lingual nodes. These nodes are not currently included in diagnostic and treatment protocols for oral tongue cancer. Combined information on surgical anatomy, clinical observations, means of detection, and prognostic value is presented. Anatomically obtained incidence of lingual nodes ranges from 8.6% to 30.2%. Incidence of lingual lymph node metastasis ranges from 1.3% to 17.1%. It is clear that lymph nodes that bear intervening tissues from the floor of the mouth should be removed to improve loco-regional control. Extended resection volume, which is required for the surgical treatment of lingual node metastasis, cannot be implied to every tongue cancer patient. As these lesions significantly influence prognosis, special efforts of their detection must be made. Reasonably, every tongue cancer patient must be investigated for the existence of lingual lymph node metastasis. Lymphographic tracing methods, which are currently implied for sentinel lymph node biopsies, may improve the detection of lingual lymph nodes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.