Evidence map›Paper›PMID 32874942›Full record

ArticleMethodsX2020

Cell-based assays to identify novel retinoprotective agents.

Jeanee Bullock, Glorivee Pagan-Mercado, S Patricia Becerra

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MethodsX, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Molecular therapy. Nucleic acids · 2025
    Article
  3. Primary Retinal Cell Cultures as a Model to Study Retina Biology.Advances in experimental medicine and biology · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jeanee BullockSection on Protein Structure and Function, LRCMB, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Glorivee Pagan-MercadoSection on Protein Structure and Function, LRCMB, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
S Patricia BecerraSection on Protein Structure and Function, LRCMB, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
National Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Degeneration of the retina can lead ultimately to devastating irreversible vision loss, such as in inherited retinitis pigmentosa and age-related macular degeneration. Currently there is no cure to prevent retinal degeneration. Quantitative cell-based assays can be used to test potential drugs that prevent the death of retinal cells

Indexed as

Automated live cell monitoringCell deathCell viabilityCytotoxicityHigh-throughput screeningNeurotrophic factorsPEDFPhotoreceptorsRetinal cells

Identifiers

PMID32874942
PMCPMC7452256
OpenAlexW3048101630

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.