Evidence map›Paper›PMID 32874938›Full record

ReviewSchizophrenia research. Cognition2020

A systematic review of research on neuropsychological measures in psychotic disorders from low and middle-income countries: The question of clinical utility.

Emmanuel K Mwesiga, Dickens Akena, Nastassja Koen, Richard Senono, Ekwaro A Obuku, Joy Louise Gumikiriza, Reuben N Robbins, Noeline Nakasujja, Dan J Stein

Abstract readReview
In one paragraph

Review in Schizophrenia research. Cognition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emmanuel K MwesigaDepartment of Psychiatry, Makerere University, Uganda.
Dickens AkenaDepartment of Psychiatry, Makerere University, Uganda.
Nastassja KoenSA MRC Research Unit on Risk & Resilience in Mental Disorders, South Africa.
Richard SenonoInfectious Disease Institute, Makerere University, Uganda.
Ekwaro A ObukuAfrica Centre for Systematic Reviews and Knowledge Translation, College of Health Sciences, Makerere University, Uganda.
Joy Louise GumikirizaDepartment of Psychiatry, Makerere University, Uganda.
Reuben N RobbinsNew York State Psychiatric Institute, Columbia University Irving Medical Center, United States of America.
Noeline NakasujjaDepartment of Psychiatry, Makerere University, Uganda.
Dan J SteinDepartment of Psychiatry and Neuroscience Institute, University of Cape Town, South Africa.

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Claude Ann Mellins · 2003 to 2026
$48.2M
NIMH NIH HHS P30 MH043520
6 · The paper itself

Abstract

introductionSeveral studies of neuropsychological measures have been undertaken in patients with psychotic disorders from low- and middle-income countries (LMICs). It is, however, unclear if the measures used in these studies are appropriate for cognitive screening in clinical settings. We undertook a systematic review to determine if measures investigated in research on psychotic disorders in LMICs meet the clinical utility criteria proposed by The Working Group on Screening and Assessment.

methodsPreferred Reporting Items for Systematic Reviews and Meta-Analyses were employed. We determined if tests had been validated against a comprehensive test battery, the duration and scope of the tests, the personnel administering the tests, and the means of administration.

resultsA total of 31 articles were included in the review, of which 11 were from Africa. The studies included 3254 participants with psychosis and 1331 controls. 3 studies reported on the validation of the test against a comprehensive cognitive battery. Assessments took 1 h or less to administer in 6/31 studies. The average number of cognitive domains assessed was four. Nonspecialized staff were used in only 3/31 studies, and most studies used pen and paper tests (17/31).

conclusionNeuropsychological measures used in research on psychotic disorders in LMICs typically do not meet the Working Group on Screening and Assessment clinical utility criteria for cognitive screening. Measures that have been validated in high-income countries but not in LMICs that do meet these criteria, such as the Brief Assessment of Cognition in Schizophrenia, therefore deserve further study in LMIC settings.

Indexed as

CognitionLow and middle-income countriesPsychosisScreeningSystematic review

Identifiers

PMID32874938
PMCPMC7451606

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.