Evidence map›Paper›PMID 32874919›Full record

ArticleToxicology reports2020

Evaluation of the protective effects of quercetin and gallic acid against oxidative toxicity in rat's kidney and HEK-293 cells.

Sunny O Abarikwu, Godwin Simple, Samuel Chimezie Onuoha, Ifeoma Mokwenye, Jean-Frances Ayogu

Abstract read
In one paragraph

Article in Toxicology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Toxicology reports · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sunny O AbarikwuDepartment of Biochemistry, Faculty of Science, University of Port Harcourt, Choba, Nigeria.
Godwin SimpleDepartment of Biochemistry, Faculty of Science, University of Port Harcourt, Choba, Nigeria.
Samuel Chimezie OnuohaDepartment of Biochemistry, Faculty of Science, University of Port Harcourt, Choba, Nigeria.
Ifeoma MokwenyeDepartment of Biochemistry, Faculty of Science, University of Port Harcourt, Choba, Nigeria.
Jean-Frances AyoguDepartment of Biochemistry, Faculty of Science, University of Port Harcourt, Choba, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quercetin and gallic acid are phytochemicals with interesting pharmacological properties. We herein investigated the protective effect of quercetin (QUE) in comparison with gallic acid (GAL) against exogenously-induced oxidative damage in rats' kidney and human embryonic kidney (HEK-293) cell lines. Adult Wistar rats were treated with QUE and GAL (50 mg/kg) separately or in combination with di-n-butylphthalate (DnBP) for 14 days; and HEK-293 cells were treated with different concentrations of GAL (25-294 μM) or QUE (2-17 μM or 28-165.43 μM) singly or in combination with H

Indexed as

AntioxidantGallic acidHEK- 293 cellsKidneyOxidative stressQuercetin

Identifiers

PMID32874919
PMCPMC7451806

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.