Evidence map›Paper›PMID 32874826›Full record

ArticlePreventive medicine reports2020

Triglyceride glucose index as a tool to motivate early lifestyle modification in young adults at diabetes risk: The Baependi Heart Study.

Camila Maciel de Oliveira, Jessica Pavani, Chunyu Liu, Rafael de Oliveira Alvim, Mercedes Balcells, Carlos Alberto Mourão-Junior, José Eduardo Krieger, Alexandre da Costa Pereira

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Preventive medicine reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Camila Maciel de OliveiraLaboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Brazil.
Jessica PavaniDepartment of Statistics, Pontificia Universidad Católica de Chile, Chile.
Chunyu LiuFramingham Heart Study, Framingham, USA.
Rafael de Oliveira AlvimLaboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Brazil.
Mercedes BalcellsGlobal CoCreation Lab, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, USA.
Carlos Alberto Mourão-JuniorDepartment of Physiology, Federal University of Juiz de Fora, Brazil.
José Eduardo KriegerLaboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Brazil.
Alexandre da Costa PereiraLaboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, Brazil.
Universidade de São Paulo · BRBoston University · USInstitut Químic de Sarrià · ESMassachusetts Institute of Technology · USPontificia Universidad Católica de Chile · CLUniversidade Federal de Juiz de Fora · BRUniversidade Federal do Amazonas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considering that the incidence of type 2 diabetes mellitus (T2DM) has been increasing especially in developing countries and becoming a global public health problem, this study aims to evaluate the association between triglyceride glucose index (TyG) - which is a mathematical product of the fasting blood glucose and triglyceride levels - and incident T2DM in an adult sample in the Baependi Heart Study (BHS). The data were from the BHS cohort consisting of two periods: cycle 1 (2005-2006; n = 1712; 119 families) and cycle 2 (2010-2013; n = 3017; 127 families). A total of 1121 individuals (both sexes, 18-100 years) were selected if they were assessed in both cycles and not diagnosed with T2DM at baseline (cycle 1). Our findings showed that a participant's risk of developing T2DM increased almost 10 times for a one-unit increase in the TyG (odds ratio OR = 10.17, 95% CI, 7.51-13.93). The association when stratified by age was OR = 28.13 [95% CI, 14.03-56.41] for young adults, meaning that the risk of developing T2DM increased more than 28 times for a one-unit increase in the TyG. For the other groups, young middle-aged adults, old middle-aged adults, and seniors, we found OR = 4.84 [95% CI, 2.91-8.06], OR = 28.73 [95% CI, 10.63-77.65, and OR = 9.88 [95% CI, 3.16-30.90], respectively. A higher TyG implies a significant increase in the risk of developing T2DM, which could be an important screening tool to target early lifestyle intervention in Brazil.

Indexed as

Baependi Heart Study cohortBMI, body mass indexBrazilCI, confidence intervalDBP, diastolic blood pressureFPG, fasting plasma glucoseGlucoseHDL, high-density lipoproteinLDL, low-density lipoproteinOR, odds ratioSBP, systolic blood pressureSD, standard deviationT2DM, type 2 diabetes mellitusTriglyceride glucose indexTriglyceridesTyG, triglyceride-glucose indexType 2 diabetes mellitusWC, waist circumference

Identifiers

PMID32874826
PMCPMC7452098
OpenAlexW3047090764

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.