Evidence map›Paper›PMID 32874673›Full record

ArticleObesity science & practice2020

Real-world persistence with liraglutide 3.0 mg for weight management and the SaxendaCare® patient support program.

Sean Wharton, Christiane L Haase, Elham Kamran, Aiden Liu, Johanna Mancini, Drew Neish, Arash Pakseresht, G Sarah Power, Rebecca Ag Christensen

Abstract read
In one paragraph

Article in Obesity science & practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Five-year Weight Loss Maintenance With Obesity Pharmacotherapy.The Journal of clinical endocrinology and metabolism · 2023
    Article
  4. Article
  5. Observational
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sean WhartonWharton Medical Clinic Burlington ON Canada.ORCID https://orcid.org/0000-0003-0111-1530
Christiane L HaaseNovo Nordisk A/S Copenhagen Denmark.
Elham KamranWharton Medical Clinic Burlington ON Canada.
Aiden LiuNovo Nordisk Canada Inc. Mississauga ON Canada.
Johanna ManciniIQVIA, Montreal QC Canada.
Drew NeishIQVIA, Montreal QC Canada.
Arash PaksereshtNovo Nordisk A/S Copenhagen Denmark.
G Sarah PowerIQVIA Mississauga ON Canada.
Rebecca Ag ChristensenWharton Medical Clinic Burlington ON Canada.ORCID https://orcid.org/0000-0001-5212-8688

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWeight management medications can significantly increase patients' chances of achieving a clinically meaningful weight loss if patients persist with treatment. This retrospective observational study of de-identified medical records of 311 patients is the first real-world study examining persistence with liraglutide 3.0 mg in Canada, and also investigates associations between the SaxendaCare® patient support program and persistence and weight loss.

methodsOverall persistence was assessed, as well as associations of enrollment in SaxendaCare®, persistence and weight loss.

resultsOverall mean (standard deviation) persistence with liraglutide 3.0 mg was 6.3 (4.1) months, and 67.5% (

conclusionsThese findings suggest that, in clinical settings, persistence with liraglutide 3.0 mg can exceed 6 months, and that enrolling in SaxendaCare® may be associated with comparatively longer persistence and, regardless of persistence, greater weight loss.

Indexed as

Liraglutide 3.0 mgobesitypersistenceSaxendaCare®

Identifiers

PMID32874673
PMCPMC7448157

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.