Evidence map›Paper›PMID 32874491›Full record

ArticleChemical science2020

Enantioselective synthesis of isochromans and tetrahydroisoquinolines by C-H insertion of donor/donor carbenes.

Leslie A Nickerson, Benjamin D Bergstrom, Mingchun Gao, Yuan-Shin Shiue, Croix J Laconsay, Matthew R Culberson, Walker A Knauss, James C Fettinger, Dean J Tantillo, Jared T Shaw

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Chemical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Ligand-controlled divergent asymmetric C(spNature communications · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Silver-catalyzed site-selective C(spNature communications · 2022
    Article
  9. Article
  10. Transition Metal Catalyzed Insertion Reactions with Donor/Donor Carbenes.Angewandte Chemie (International ed. in English) · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. C-H Insertion Reactions of Donor/Donor Carbenes: Inception, Investigation, and Insights.Synlett : accounts and rapid communications in synthetic organic chemistry · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Leslie A NickersonChemistry Department , University of California, Davis , One Shields Ave , Davis , CA 95616 , USA . Email: jtshaw@ucdavis.edu.ORCID 0000-0002-4079-3514
Benjamin D BergstromChemistry Department , University of California, Davis , One Shields Ave , Davis , CA 95616 , USA . Email: jtshaw@ucdavis.edu.ORCID 0000-0003-2179-1334
Mingchun GaoChemistry Department , University of California, Davis , One Shields Ave , Davis , CA 95616 , USA . Email: jtshaw@ucdavis.edu.ORCID 0000-0002-8564-4387
Yuan-Shin ShiueChemistry Department , University of California, Davis , One Shields Ave , Davis , CA 95616 , USA . Email: jtshaw@ucdavis.edu.ORCID 0000-0003-2493-4329
Croix J LaconsayChemistry Department , University of California, Davis , One Shields Ave , Davis , CA 95616 , USA . Email: jtshaw@ucdavis.edu.ORCID 0000-0002-9244-1318
Matthew R CulbersonChemistry Department , University of California, Davis , One Shields Ave , Davis , CA 95616 , USA . Email: jtshaw@ucdavis.edu.ORCID 0000-0001-8372-1177
Walker A KnaussChemistry Department , University of California, Davis , One Shields Ave , Davis , CA 95616 , USA . Email: jtshaw@ucdavis.edu.ORCID 0000-0002-1680-7904
James C FettingerChemistry Department , University of California, Davis , One Shields Ave , Davis , CA 95616 , USA . Email: jtshaw@ucdavis.edu.ORCID 0000-0002-6428-4909
Dean J TantilloChemistry Department , University of California, Davis , One Shields Ave , Davis , CA 95616 , USA . Email: jtshaw@ucdavis.edu.ORCID 0000-0002-2992-8844
Jared T ShawChemistry Department , University of California, Davis , One Shields Ave , Davis , CA 95616 , USA . Email: jtshaw@ucdavis.edu.ORCID 0000-0001-5190-493X
Division of Chemistry · US

Funding

Synthesis of Diverse Natural Products and Complex Heterocycles with Donor/Donor CarbenoidsR01GM124234 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SHAW, JARED THOMAS · 2018 to 2021
$1.3M
NIGMS NIH HHS R01 GM124234
6 · The paper itself

Abstract

Reports of C-H insertions forming six-membered rings containing heteroatoms are rare due to Stevens rearrangements occurring after nucleophilic attack on the carbene by a heteroatom. Using donor/donor carbenes and Rh

Identifiers

PMID32874491
PMCPMC7439777
OpenAlexW2984935654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.