Evidence map›Paper›PMID 32874406›Full record

ArticleThe Pan African medical journal2020

Isolated blast crisis relapse in the central nervous system of a patient treating for a chronic myelogenous leukemia.

Houda Boudiaf, Khedaoudj Ezziane, Nassiba Ould Rouis, Meriem Himrane, Saliha Hakem, Hanifa Benchabane, Houria Boukhelal, Radja Arous, Lynda Chikhi

Open access · goldAbstract readCase Reports
In one paragraph

Article in The Pan African medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Houda BoudiafDepartment of Pediatric Oncology, University Hospital of Mustapha Pacha, Algiers, Algeria.
Khedaoudj EzzianeDepartment of Pediatric Oncology, University Hospital of Mustapha Pacha, Algiers, Algeria.
Nassiba Ould RouisDepartment of Pediatric Oncology, University Hospital of Mustapha Pacha, Algiers, Algeria.
Meriem HimraneDepartment of Pediatric Oncology, University Hospital of Mustapha Pacha, Algiers, Algeria.
Saliha HakemDepartment of Pediatric Oncology, University Hospital of Mustapha Pacha, Algiers, Algeria.
Hanifa BenchabaneDepartment of Pediatric Oncology, University Hospital of Mustapha Pacha, Algiers, Algeria.
Houria BoukhelalDepartment of Pediatric Oncology, University Hospital of Mustapha Pacha, Algiers, Algeria.
Radja ArousDepartment of Pediatric Oncology, University Hospital of Mustapha Pacha, Algiers, Algeria.
Lynda ChikhiDepartment of Blood Transfusion and Hemobiology, University Hospital of Mustapha Pacha, Algiers, Algeria.
Hôpital Mustapha Pacha · DZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic myeloid leukemia (CML) is a myeloproliferative disorder associated with the Philadelphia chromosome t (9;22) and the BCR-ABL fusion gene. The condition is relatively rare, accounting for 2.0% to 3.0% of childhood leukemia cases. CML has historically been a triphasic disease. Most patients are diagnosed in chronic phase. Without treatment, it inevitably progresses into a more aggressive accelerated phase and blast crisis. Some proportion of CML cases of blastic transformation develop an extramedullary disease that involves rarely central nervous system. This report describe an extremely rare case of 13-year-old girl with CML and extramedullary blast crisis in the central nervous system. Treatment options and monitoring of disease response are discussed.

Indexed as

AdolescentAlgeriaAntineoplastic Combined Chemotherapy ProtocolsBlast CrisisCentral Nervous SystemFemaleHumansImatinib MesylateLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLeukemic InfiltrationRecurrenceImatinib Mesylateblast crisiscentral nervous systemChronic myeloid leukemiaimatinib

Identifiers

PMID32874406
PMCPMC7436633
OpenAlexW3038567063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.