ArticleEFSA journal. European Food Safety Authority2020
Cumulative dietary risk characterisation of pesticides that have chronic effects on the thyroid.
Article in EFSA journal. European Food Safety Authority, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
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- Overview of Current Regulatory and Methodological Approaches for the Risk Assessment of Mycotoxins.Toxins · 2026Review
- The 2024 European Union report on pesticide residues in food.EFSA journal. European Food Safety Authority · 2026Article
- Pesticide prioritization based on risk and model diet proposals for assessing cumulative exposure to pesticide residues in the Brazilian population through food consumption.Pest management science · 2026Article
- Review
- Risk Assessment of Chemical Mixtures in Foods: A Comprehensive Methodological and Regulatory Review.Foods (Basel, Switzerland) · 2026Review
- Health Risk Assessment of Dietary Chemical Exposures: A Comprehensive Review.Foods (Basel, Switzerland) · 2025Review
- Advancing the One Health Framework in EU Plant Protection Product Regulation: Challenges and Opportunities.Journal of xenobiotics · 2025Article
- Specific effects on the reproductive function including fertility relevant for cumulative risk assessment of pesticide residues.EFSA journal. European Food Safety Authority · 2025Article
- Urinary Biomonitoring of Mycotoxins in Spanish Adults: Predictors of Exposure and Health Risk Evaluation.Toxics · 2025Article
- Chemical Food Safety in Europe Under the Spotlight: Principles, Regulatory Framework and Roadmap for Future Directions.Foods (Basel, Switzerland) · 2025Review
- Specific effects on kidneys relevant for performing a dietary cumulative risk assessment of pesticide residues.EFSA journal. European Food Safety Authority · 2025Article
- Specific effects on liver relevant for performing a dietary cumulative risk assessment of pesticide residues.EFSA journal. European Food Safety Authority · 2025Article
- The 2023 European Union report on pesticide residues in food.EFSA journal. European Food Safety Authority · 2025Article
- Probabilistic assessment of the cumulative risk from dietary heavy metal exposure in Chongqing, China using a hazard-driven approach.Scientific reports · 2025Article
- The Need for an Alternative Health Claim Process for Foods Based on Both Nutrient and Contaminant Profiles.Current developments in nutrition · 2024Article
- Specific effects on the thyroid relevant for performing a dietary cumulative risk assessment of pesticide residues: 2024 update.EFSA journal. European Food Safety Authority · 2024Article
- Prioritisation of pesticides and target organ systems for dietary cumulative risk assessment based on the 2019-2021 monitoring cycle.EFSA journal. European Food Safety Authority · 2024Article
- Cumulative risk assessment with pesticides in the framework of MRL setting.EFSA journal. European Food Safety Authority · 2023Article
- New approach methodologies in human regulatory toxicology - Not if, but how and when!Environment international · 2023Review
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A retrospective chronic cumulative risk assessment of dietary exposure to pesticide residues, supported by an uncertainty analysis based on expert knowledge elicitation, was conducted for two effects on the thyroid, hypothyroidism and parafollicular cell (C-cell) hypertrophy, hyperplasia and neoplasia. The pesticides considered in this assessment were identified and characterised in the scientific report on the establishment of cumulative assessment groups of pesticides for their effects on the thyroid. Cumulative exposure assessments were conducted through probabilistic modelling by EFSA and the Dutch National Institute for Public Health and the Environment (RIVM) using two different software tools and reported separately. These exposure assessments used monitoring data collected by Member States under their official pesticide monitoring programmes in 2014, 2015 and 2016 and individual consumption data from 10 populations of consumers from different countries and different age groups. This report completes the characterisation of cumulative risk, taking account of the available data and the uncertainties involved. For each of the 10 populations, it is concluded with varying degrees of certainty that cumulative exposure to pesticides that have the chronic effects on the thyroid mentioned above does not exceed the threshold for regulatory consideration established by risk managers.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.