Evidence map›Paper›PMID 32874256›Full record

ArticleEFSA journal. European Food Safety Authority2020

Risk assessment of aflatoxins in food.

EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús Del Mazo, Bettina Grasl-Kraupp, Christer Hogstrand, Laurentius Ron Hoogenboom, Jean-Charles Leblanc and 15 more

Open access · diamondAbstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 232 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
232citing papers in PubMed, 6 pooled it
57.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

232 citing papers in PubMed, 6 syntheses or guidelines pooled it, 441 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Article
  8. Aflatoxin MMolecules (Basel, Switzerland) · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

172 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

EFSA Panel on Contaminants in the Food Chain (CONTAM)
Dieter Schrenk
Margherita Bignami
Laurent Bodin
James Kevin Chipman
Jesús Del Mazo
Bettina Grasl-Kraupp
Christer Hogstrand
Laurentius Ron Hoogenboom
Jean-Charles Leblanc
Carlo Stefano Nebbia
Elsa Nielsen
Evangelia Ntzani
Annette Petersen
Salomon Sand
Tanja Schwerdtle
Christiane Vleminckx
Doris Marko
Isabelle P Oswald
Aldert Piersma
Michael Routledge
Josef Schlatter
Katleen Baert
Petra Gergelova
Heather Wallace

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

EFSA was asked to deliver a scientific opinion on the risks to public health related to the presence of aflatoxins in food. The risk assessment was confined to aflatoxin B1 (AFB1), AFB2, AFG1, AFG2 and AFM1. More than 200,000 analytical results on the occurrence of aflatoxins were used in the evaluation. Grains and grain-based products made the largest contribution to the mean chronic dietary exposure to AFB1 in all age classes, while 'liquid milk' and 'fermented milk products' were the main contributors to the AFM1 mean exposure. Aflatoxins are genotoxic and AFB1 can cause hepatocellular carcinomas (HCCs) in humans. The CONTAM Panel selected a benchmark dose lower confidence limit (BMDL) for a benchmark response of 10% of 0.4 μg/kg body weight (bw) per day for the incidence of HCC in male rats following AFB1 exposure to be used in a margin of exposure (MOE) approach. The calculation of a BMDL from the human data was not appropriate; instead, the cancer potencies estimated by the Joint FAO/WHO Expert Committee on Food Additives in 2016 were used. For AFM1, a potency factor of 0.1 relative to AFB1 was used. For AFG1, AFB2 and AFG2, the

Indexed as

aflatoxincancerexposurefoodlivermargin of exposure (MOE)occurrence

Identifiers

PMID32874256
PMCPMC7447885
OpenAlexW3010056058

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.