Evidence map›Paper›PMID 32873991›Full record

ArticleActa histochemica et cytochemica2020

Fatty Acid Binding Protein 7 is Involved in the Proliferation of Reactive Astrocytes, but not in Cell Migration and Polarity.

Tomonori Hara, Banlanjo Abdulaziz Umaru, Kazem Sharifi, Takeo Yoshikawa, Yuji Owada, Yoshiteru Kagawa

Open access · diamondAbstract read
In one paragraph

Article in Acta histochemica et cytochemica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Tomonori HaraDepartment of Organ Anatomy, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Banlanjo Abdulaziz UmaruDepartment of Organ Anatomy, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Kazem SharifiDepartment of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Takeo YoshikawaLaboratory for Molecular Psychiatry, RIKEN Center for Brain Science, Wako 351-0198, Japan.
Yuji OwadaDepartment of Organ Anatomy, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Yoshiteru KagawaDepartment of Organ Anatomy, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Tohoku University · JPRIKEN Center for Brain Science · JPShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive gliosis is a defense mechanism to minimize and repair the initial damage after CNS injuries that is characterized by increases in astrocytic reactivity and proliferation, with enhanced expression of glial fibrillary acidic protein (GFAP) and cellular hypertrophy. Fatty acid binding protein 7 (FABP7) is abundantly expressed in several types of glial cells, such as astrocytes and oligodendrocyte precursor cells, during brain development and FABP7-positive astrocytes have been shown to be significantly increased in the mouse cortex after a stab injury. However, the functional significance of FABP7 in gliosis remains unclear. In the present study, we examined the mechanism of FABP7-mediated regulation of gliosis using an

Indexed as

fatty acid binding protein 7migrationpolarityproliferationreactive astrocyte

Identifiers

PMID32873991
PMCPMC7450179
OpenAlexW3038989103

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.