Evidence map›Paper›PMID 32873959›Full record

ArticleEuropean journal of clinical nutrition2020

Estimates of renal net acid excretion and their relationships with serum uric acid and hyperuricemia in a representative German population sample.

Jonas Esche, Danika Krupp, Gert Bm Mensink, Thomas Remer

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Article in European journal of clinical nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jonas EscheDONALD Study Center Dortmund, IEL - Nutritional Epidemiology, University of Bonn, Dortmund, Germany.
Danika KruppDONALD Study Center Dortmund, IEL - Nutritional Epidemiology, University of Bonn, Dortmund, Germany.
Gert Bm MensinkDepartment of Epidemiology and Health Monitoring, Robert Koch-Institute, Berlin, Germany.
Thomas RemerDONALD Study Center Dortmund, IEL - Nutritional Epidemiology, University of Bonn, Dortmund, Germany. remer@uni-bonn.de.
TU Dortmund University · DERobert Koch Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivePreliminary interventional data suggest that a reduction of dietary acid load raises renal uric acid excretion and decreases serum uric acid (SUA). In line with this, in a recent cross-sectional analysis of a representative adult population sample, a higher potential renal acid load (PRAL) was found to associate with higher SUA levels. Against this background, we re-examined the relationship of the body's acid load with SUA and hyperuricemia using nutrition-derived estimates of renal net acid excretion (NAE). SUBJECTS/

methodsCross-sectional analyses were performed in n = 6894 participants (18-79 y) of the German Health Interview and Examination Survey for Adults (DEGS1). Two different approaches were used to estimate NAE, one based on the sum of food frequency questionnaire (FFQ)-derived PRAL and body-surface area-derived organic acids (eNAE

resultsAfter adjusting for relevant confounders, eNAE

conclusionThe results substantiate findings of a previous analysis that dietary acid load is a potential influencing factor on SUA. This implicates that a lower dietary acid load may have beneficial effects on SUA.

Indexed as

HyperuricemiaUric AcidAcidsAdultCross-Sectional StudiesHumansRenal EliminationRisk FactorsAcidsUric Acid

Identifiers

PMID32873959
OpenAlexW3082543073

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.