Evidence map›Paper›PMID 32873946›Full record

ArticleEye (London, England)2021

Analysis of optical coherence angiography in cystoid macular oedema associated with gyrate atrophy.

Ahmad M Mansour, Ayman G Elnahry, Koushik Tripathy, Robert E Foster, Carl-Jo Mehanna, Raval Vishal, Cemal Çavdarlı, Alessandro Arrigo, Maurizio Battaglia Parodi

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Eye (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 5 countries.

Ahmad M MansourDepartment of Ophthalmology, American University of Beirut, Beirut, Lebanon. ammansourmd@gmail.com.ORCID http://orcid.org/0000-0001-8430-2214
Ayman G ElnahryDepartment of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt.ORCID http://orcid.org/0000-0001-5148-316X
Koushik TripathyDepartment of Ophthalmology, Department of Retina and Uvea, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.ORCID http://orcid.org/0000-0002-9756-128X
Robert E FosterDepartment of Ophthalmology, University of Cincinnati, CIncinnati Eye Institute, Cincinnati, OH, USA.
Carl-Jo MehannaDepartment of Ophthalmology, American University of Beirut, Beirut, Lebanon.
Raval VishalL.V. Prasad Eye Institute, Kode Venkatadri Chowdary Campus, Tadigadapa, India.
Cemal ÇavdarlıDepartment of Ophthalmology, Ankara City Hospital, MHC Blok Bilent University, Ankara, Turkey.
Alessandro ArrigoDepartment of Ophthalmology Ospedale San Raffaele, University Vita-Salute Milan, Milano, Italy.
Maurizio Battaglia ParodiDepartment of Ophthalmology Ospedale San Raffaele, University Vita-Salute Milan, Milano, Italy. maubp@yahoo.it.
American University of Beirut · LBCairo University · EGCincinnati Eye Institute · USL V Prasad Eye Institute · INManhattan Eye, Ear and Throat Hospital · USRafik Hariri University Hospital · LBUniversity of Messina · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the relationship between superficial, deep foveal avascular zone (FAZ) and foveal cyst areas in eyes with cystoid macular oedema (CMO) associated with gyrate atrophy of the choroid and retina (GA).

methodsThis is a retrospective collaborative multicenter study of optical coherence tomography-angiography (OCTA) images in GA. Superficial and deep FAZ and foveal cyst were measured using Image J by two independent experts. Values were corrected for myopia magnification. These values were compared with age-matched controls from normative data.

resultsTwenty-three eyes from 12 patients with GA and CMO were included in the study. The mean ± standard deviation age was 22 ± 19.7 years, mean Snellen spectacle-corrected visual acuity of 20/70 with mean myopia of 5.7 ± 4.1 dioptres. Qualitatively, no focal occlusion of superficial and deep capillary plexus was noted. Mean superficial FAZ area (0.484 ± 0.317 mm

conclusionsThe superficial and deep FAZ area in GA-associated CMO were noted to be significantly larger than in controls. It seems that RPE dysfunction leads to foveal cyst enlargement displacing the capillary plexus with resultant enlarged superficial and deep FAZ area.

Indexed as

Gyrate AtrophyMacular EdemaAdolescentAdultChildChild, PreschoolFluorescein AngiographyFovea CentralisHumansRetinal VesselsRetrospective StudiesTomography, Optical CoherenceYoung Adult

Identifiers

PMID32873946
PMCPMC8169820
OpenAlexW3082295051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.