Evidence map›Paper›PMID 32873917›Full record

ReviewProstate cancer and prostatic diseases2021

Animal models of benign prostatic hyperplasia.

Junjie Zhang, Mengda Zhang, Jin Tang, Guangming Yin, Zhi Long, Leye He, Chuanchi Zhou, Lufeng Luo, Lin Qi, Long Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Prostate cancer and prostatic diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Pharmaceuticals (Basel, Switzerland) · 2026
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  10. Cellular cartography reveals mouse prostate organization and determinants of castration resistance.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Junjie ZhangDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Mengda ZhangDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Jin TangDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Guangming YinDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Zhi LongDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Leye HeDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Chuanchi ZhouDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Lufeng LuoDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.
Lin QiDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Long WangDepartment of Urology, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China. wanglong@csu.edu.cn.ORCID http://orcid.org/0000-0003-4583-2428
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms are common clinical concerns that affect aging men all over the world. The underlying molecular and cellular mechanisms remain elusive. Over the past few years, a number of animal models of BPH, including spontaneous model, BPH-induction model, xenograft model, metabolic syndrome model, mechanical obstruction model, and transgenic model, have been established that may provide useful tools to fill these critical knowledge gaps. In this review, we therefore outlined the present status quo for animal models of BPH, comparing the pros and cons with respect to their ability to mimic the etiological, histological, and clinical hallmarks of BPH and discussed their applicability for future research.

Indexed as

AnimalsDisease Models, AnimalGlobal HealthIncidenceMaleProstatic HyperplasiaRisk Assessment

Identifiers

PMID32873917
OpenAlexW3082805365

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.