ArticleRespiratory care2021
Preserved Ratio Impaired Spirometry in a Spirometry Database.
Article in Respiratory care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed, 5 syntheses or guidelines pooled it, 104 citations in OpenAlex.
- Comprehensive application of artificial intelligence in preserved ratio impaired spirometry: A systematic literature review.PloS one · 2026Pooled it
- Pooled it
- Prevalence of chronic respiratory disease using case-finding tools in adults living with noncommunicable disease in low- and middle-income countries: a systematic review.BMC pulmonary medicine · 2025Pooled it
- Association of preserved ratio impaired spirometry with mortality and cardiovascular diseases: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- Criteria for Enrollment of Patients With COPD in Palliative Care Trials: A Systematic Review.Journal of pain and symptom management · 2024Pooled it
- Significant Spirometric Transitions and Preserved Ratio Impaired Spirometry Among Ever Smokers.Chest · 2022Trial
- Normal spirometry with high and asthma-defining bronchodilator responsiveness: An appraisal from real-life data.Lung India : official organ of Indian Chest Society · 2026Article
- Prevalence of PRISm and COPD and associated factors in a university medical centre spirometry unit: a cross-sectional analysis.BMJ open · 2026Article
- Impact of preserved ratio impaired spirometry on postoperative outcomes of non-small cell lung cancer surgery.Scientific reports · 2026Article
- Multimodal data-driven multitask learning for enhanced identification and classification of chronic obstructive pulmonary disease: a retrospective study.Journal of global health · 2026Article
- The Inflammation-Metabolism Axis in Preserved Ratio Impaired Spirometry: Pathogenic Mechanisms and Translational Implications.Journal of inflammation research · 2026Review
- Clinical characteristics and outcomes associated with preserved ratio impaired spirometry (PRISm) in Saudi Arabia.Frontiers in medicine · 2026Article
- PulmoClass-3DAtt: A Self-Attention Network for Classification of COPD, PRISm and Normal.International journal of chronic obstructive pulmonary disease · 2026Article
- The joint association between inflammation and centripedal obesity with mortality risk in patients with preserved ratio impaired spirometry.NPJ primary care respiratory medicine · 2025Article
- Preserved Ratio Impaired Spirometry (PRISm) from an Epidemiological Perspective.Journal of clinical medicine · 2025Article
- Impulse oscillometry for the detection of small airway dysfunction in patients with chronic respiratory symptoms, preserved ratio impaired spirometry and COPD.BMC pulmonary medicine · 2025Article
- Assessment of Small Airways Function in Eosinophilic Preserved Ratio Impaired Spirometry.Pulmonary therapy · 2025Article
- Preserved ratio impaired spirometry, dysanapsis and airflow obstruction with low forced expiratory volume in 1 s in childhood asthma.ERJ open research · 2025Article
- PRISm and the risk for all-cause mortality in relation to sleep disordered breathing: a community-based study.ERJ open research · 2025Article
- Increased risk of lung cancer in individuals with preserved ratio impaired spirometry: a nationwide cohort study.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSpirometry results can yield a diagnosis of normal air flow, air flow obstruction, or preserved ratio impaired spirometry (PRISm), defined as a reduced FEV
methodsWe performed a retrospective analysis of 21,870 spirometries; 1,616 were excluded because of missing data or extremes of age, height, or weight. We calculated the prevalence of PRISm in prebronchodilator and postbronchodilator pulmonary function tests. Subsequently, we calculated the prevalence of PRISm by various age, race, body mass index, and diagnosis categories, as well as by gender and smokers versus nonsmokers. Finally, in the subset of the cohort with FEV
resultsWe identified 18,059 prebronchodilator spirometries, and 22.3% of these yielded a PRISm diagnosis. This prevalence remained stable in postbronchodilator spirometries (17.7%), after excluding earlier pulmonary function tests for subjects with multiple pulmonary function tests (20.7% in prebronchodilator and 24.3% in postbronchodilator), and when we limited the analysis to prebronchodilator spirometries that met American Thoracic Society criteria (20.6%). The PRISm prevalence was higher in subjects 45-60 y old (24.4%) and in males (23.7%) versus females (17.9%). The prevalence rose with body mass index and was higher for those with a referral diagnosis of restrictive lung disease (50%). PRISm prevalence was similar between races and smokers versus nonsmokers. In a multivariable analysis, higher % of predicted FEV
conclusionsIn a spirometry database at an academic medical center, the PRISm prevalence was 17-24%, which is higher than previously reported.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.