Evidence map›Paper›PMID 32873333›Full record

ArticleParasites & vectors2020

National mapping of soil-transmitted helminth and schistosome infections in Ethiopia.

Gemechu Tadesse Leta, Kalkidan Mekete, Yonas Wuletaw, Abeba Gebretsadik, Heven Sime, Sindew Mekasha, Adugna Woyessa, Oumer Shafi, Jozef Vercruysse, Jack E T Grimes and 6 more

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Article in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Gemechu Tadesse LetaEthiopian Public Health Institute, PO Box 1242/5654, Addis Ababa, Ethiopia. gemechut_2006@yahoo.com.ORCID http://orcid.org/0000-0001-7623-5381
Kalkidan MeketeEthiopian Public Health Institute, PO Box 1242/5654, Addis Ababa, Ethiopia.
Yonas WuletawEthiopian Public Health Institute, PO Box 1242/5654, Addis Ababa, Ethiopia.
Abeba GebretsadikEthiopian Public Health Institute, PO Box 1242/5654, Addis Ababa, Ethiopia.
Heven SimeEthiopian Public Health Institute, PO Box 1242/5654, Addis Ababa, Ethiopia.
Sindew MekashaEthiopian Public Health Institute, PO Box 1242/5654, Addis Ababa, Ethiopia.
Adugna WoyessaEthiopian Public Health Institute, PO Box 1242/5654, Addis Ababa, Ethiopia.
Oumer ShafiFederal Ministry of Health, PO Box 1234, Addis Ababa, Ethiopia.
Jozef VercruysseDepartment of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Jack E T GrimesDepartment of Civil and Environmental Engineering, South Kensington Campus, Imperial College London, London, SW7 2AZ, UK.
Iain GardinerPartnership for Child Development, Department of Infectious Disease Epidemiology, St Mary's Campus, Imperial College London, London, W2 1PG, UK.
Michael FrenchSchistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, St Mary's Campus, Imperial College London, London, W2 1PG, UK.
Bruno LeveckeDepartment of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Lesley DrakePartnership for Child Development, Department of Infectious Disease Epidemiology, St Mary's Campus, Imperial College London, London, W2 1PG, UK.
Wendy HarrisonSchistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, St Mary's Campus, Imperial College London, London, W2 1PG, UK.
Alan FenwickSchistosomiasis Control Initiative, Department of Infectious Disease Epidemiology, St Mary's Campus, Imperial College London, London, W2 1PG, UK.

Funding

Schistosomiasis Control Initiative and Partnership for child development P43436
6 · The paper itself

Abstract

backgroundAn accurate understanding of the geographical distributions of both soil-transmitted helminths (STHs; Ascaris lumbricoides, Trichuris trichiura, and the hookworms Necator americanus and Ancylostoma duodenale) and schistosomes (SCH; Schistosoma mansoni and S. haematobium) is pivotal to be able to effectively design and implement mass drug administration (MDA) programmes. The objective of this study was to provide up-to-date data on the distribution of both STH and SCH in Ethiopia to inform the design of the national control program and to be able to efficiently achieve the 75% MDA coverage target set by the WHO.

methodsBetween 2013 and 2015, we assessed the distributions of STH and SCH infections in a nationwide survey covering 153,238 school-aged children (aged 5-15 years), from 625 woredas (districts), representing all nine Regional States and two City Administrations of Ethiopia. Nationwide disease maps were developed at the woreda level to enable recommendations on the design of the national MDA programme.

resultsThe prevalence of any STH infection across the study population was 21.7%, with A. lumbricoides (12.8%) being the most prevalent STH, followed by hookworms (7.6%) and T. trichiura (5.9%). The prevalence for any SCH was 4.0% in areas where both SCH species were evaluated. Schistosoma mansoni was the most prevalent SCH (3.5 vs 0.3%). STHs were more prevalent in southwest Ethiopia, whereas SCH was found mostly in the west and northeast of the country. The prevalence of moderate-to-heavy intensity infections was 2.0% for STHs and 1.6% for SCH. For STH, a total of 251 woredas were classified as moderately (n = 178) or highly endemic (n = 73), and therefore qualify for an annual and biannual MDA program, respectively. For SCH, 67 woredas were classified as endemic and 8 as highly endemic, and hence they require every two years and annual MDA programme, respectively.

conclusionsThe results confirm that Ethiopia is endemic for both STHs and SCH, posing a significant public health problem. Following the WHO recommendations on mass drug administration, 18 and 14 million school-aged children are in need of MDA for STHs and SCH, respectively, based on the number of SACs that live on the eligible geographical areas.

Indexed as

AdolescentAncylostomatoideaAnimalsAnthelminticsAscaris lumbricoidesChildChild, PreschoolCross-Sectional StudiesEpidemiological MonitoringEthiopiaFemaleHelminthiasisHelminthsHumansMaleMass Drug AdministrationAnthelminticsSoilAscarisDisease mapsEndemicityhookwormsMass drug administrationSchistosoma haematobiumSchistosoma mansoniSchistosomiasisSchool-aged childrenSoil-transmitted helminthiasisTrichurisWoreda (districts)

Identifiers

PMID32873333
PMCPMC7466696

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.