ArticleBMC oral health2020
Effect of different doses of radiation on morphogical, mechanical and chemical properties of primary and permanent teeth-an in vitro study.
Article in BMC oral health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- Oral microbiota associated with radiation-related caries among nasopharyngeal carcinoma patients following radiation therapy: analysis based on a longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Dose-Dependent Effects of Simulated Clinical Radiotherapy on the Structure and Properties of Root Dentine.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Article
- Investigations of Effects of Radiotherapy, Sonic Activation and Root Canal Treatment on Fracture Resistance of Mandibular Anterior Teeth: An In Vitro Study.Journal of clinical medicine · 2026Article
- The reinforcing effect of anti-caries treatments on acidic challenge resistance of irradiated enamel.PloS one · 2026Article
- Effect of gamma radiation on human enamel chemical and physical properties.BMC oral health · 2025Article
- Evaluating microbial regulation as a preventive strategy for radiation-related caries: A review.Head & face medicine · 2025Review
- Microshear bond strength of conventional and bioactive restorative materials to irradiated and non-irradiated dentin: an in vitro study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Effect of Gamma Radiation on the Wear Potential of Hybrid Ceramic to Tooth Enamel.Materials (Basel, Switzerland) · 2025Article
- Article
- Effects of radiotherapy dose and application time on the load-to-failure values of teeth filled with different sealers.BMC oral health · 2024Article
- Updates on Caries Risk Assessment-A Literature Review.Dentistry journal · 2024Review
- Effect of different approaches of direct radiation on the surface structure and caries susceptibility of enamel.Scientific reports · 2024Article
- Evaluation and Comparison of the Dose Received by the Mandible, Maxilla, and Teeth in Two Methods of Three-dimensional Conformal Radiation Therapy and Helical Tomotherapy.Journal of medical signals and sensors · 2024Article
- Oral Complications from Oropharyngeal Cancer Therapy.Cancers · 2023Review
- Color stability and microhardness alteration of irradiated dental enamel treated with a high fluoride concentration toothpaste.Clinical oral investigations · 2022Article
- Over 300 Radiation Caries Papers: Reflections From the Rearview Mirror.Frontiers in oral health · 2022Review
- Direct Induced Effects of Standard and Modified Radiotherapy Protocol on Surface Structure of Hard Dental Tissue.Acta stomatologica Croatica · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundRadiotherapy, applied to the head and neck region, can cause radiation side effects such as reduction of saliva and radiation caries. The aim of this study was to perform an in vitro assessment of the effects of radiation therapy on the morphological, mechanical, and chemical properties of primary and permanent teeth.
methodsOne hundred four extracted human teeth (52 impacted wisdom teeth, 52 primary molar teeth) were used. The teeth were divided into two parts in the mesiodistal direction. Of the 98 teeth, the vestibular sections were used for the vickers analysis and lingual sections were used for the Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES) analysis. The teeth in the experimental group were fixed to wax models. Each model had an equal number of teeth (n = 7). The doses were applied to the teeth for 6 weeks; 5 week days and 2Gy daily. After the radiotherapy was conducted weekly, a wax model was taken from radiation reception. Along with the elemental contents (Na, K, Mg, P, and Ca) of the teeth, enamel and dentin microhardness was evaluated, and SEM analyzes were performed on 6 teeth.
resultsRadiation caused a decrease in microhardness of enamel and dentin (p < 0.05). In the elemental analysis by ICP-OES, it was observed that there were decreases in all elements after 60Gy compared to the control group (p < 0.05). In the experimental groups, amorphous structures were encountered in SEM images.
conclusionsRadiation has negative effects on the teeth structure and additional studies are needed in this regard. This study indicates that radiotherapy patients are at a higher risk for dental caries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.