ArticleBMC genomics2020
Effect of recent and ancient inbreeding on production and fertility traits in Canadian Holsteins.
Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.
- Pooled it
- Pedigree-based evaluation of classical, ancestral, and new inbreeding coefficients in Carora and Criollo Limonero dairy cattle populations.Veterinary world · 2026Article
- Heat-load-dependent inbreeding depression for production traits in Italian Holstein cattle.Genetics, selection, evolution : GSE · 2026Article
- Selection index for genetic improvement of beef performance in Huaxi cattle of Xinjiang, China.BMC genomics · 2026Article
- Probabilities of two alleles being identity by state at unobserved loci predicted by observed loci in cattle populations.Scientific reports · 2026Article
- Runs of homozygosity in Italian Holstein bulls: a permutation approach and time-based mapping of the genomic regions potentially under selection.BMC genomics · 2026Article
- Estimating Linkage Disequilibrium and Effective Population Size Across Generations in Holstein Cattle.Veterinary medicine and science · 2025Article
- Efficiency of Recurrent Genomic Selection in Panmictic Populations.Animals : an open access journal from MDPI · 2025Article
- Single-Step Breeding Value Estimations and Optimum Contribution Selection in Endangered Dual-Purpose German Black Pied Cattle (DSN) Using a Breed Specific SNP Chip.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2025Article
- Article
- Estimation of Inbreeding Depression From Overdominant Loci Using Molecular Markers.Evolutionary applications · 2025Article
- Combining genomics and semen microbiome increases the accuracy of predicting bull prolificacy.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2025Article
- Inbreeding depression for litter size in two mice lines under divergent selection for environmental birth weight variability using genomic data.Journal of animal science · 2025Article
- Ecuadorian Holstein-Friesian cattle paternal lineages: Demographic structure, inbreeding evolution, and genetic diversity.PloS one · 2025Article
- Assessment of inbreeding coefficients and inbreeding depression on complex traits from genomic and pedigree data in Nelore cattle.BMC genomics · 2024Article
- β-Defensin gene copy number variation in cattle.Royal Society open science · 2024Article
- Article
- Inbreeding depression is associated with recent homozygous-by-descent segments in Belgian Blue beef cattle.Genetics, selection, evolution : GSE · 2024Article
- Effect of Individual Rate of Inbreeding, Recent and Ancestral Inbreeding on Wool Quality, Muscling Conformation and Exterior in German Sheep Breeds.Animals : an open access journal from MDPI · 2023Article
- Genome-wide landscape of runs of homozygosity and differentiation across Egyptian goat breeds.BMC genomics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPhenotypic performances of livestock animals decline with increasing levels of inbreeding, however, the noticeable decline known as inbreeding depression, may not be due only to the total level of inbreeding, but rather could be distinctly associated with more recent or more ancient inbreeding. Therefore, splitting inbreeding into different age classes could help in assessing detrimental effects of different ages of inbreeding. Hence, this study sought to investigate the effect of recent and ancient inbreeding on production and fertility traits in Canadian Holstein cattle with both pedigree and genomic records. Furthermore, inbreeding coefficients were estimated using traditional pedigree measure (F
resultsInbreeding depression was found for all production and most fertility traits, for example, every 1% increase in F
conclusionsInbreeding depression was observed for production and fertility traits. In general, recent inbreeding had unfavorable effects, while ancestral inbreeding had favorable effects. Given that more negative effects were estimated from recent inbreeding when compared to ancient inbreeding suggests that recent inbreeding should be the primary focus of selection programs. Also, further work to identify specific recent homozygous regions negatively associated with phenotypic traits could be investigated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.