Evidence map›Paper›PMID 32873113›Full record

ArticleJournal of the American Heart Association2020

Clinical Associations of Vascular Stiffness, Microvascular Dysfunction, and Prevalent Cardiovascular Disease in a Black Cohort: The Jackson Heart Study.

Leroy L Cooper, Solomon K Musani, Josiah A Moore, Victoria A Clarke, Yuichiro Yano, Keith Cobbs, Connie W Tsao, Javed Butler, Michael E Hall, Naomi M Hamburg and 4 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Leroy L CooperDepartment of Biology Vassar College Poughkeepsie NY.
Solomon K MusaniDepartment of Medicine Division of Cardiovascular Diseases University of Mississippi Medical Center Jackson MS.
Josiah A MooreDepartment of Medicine Division of Cardiovascular Diseases University of Mississippi Medical Center Jackson MS.
Victoria A ClarkeDepartment of Biology Vassar College Poughkeepsie NY.
Yuichiro YanoDepartment of Family Medicine and Community Health Duke University Durham NC.
Keith CobbsDepartment of Medicine Division of Cardiovascular Diseases University of Mississippi Medical Center Jackson MS.
Connie W TsaoBoston University and NHLBI's Framingham Heart Study Framingham MA.
Javed ButlerDepartment of Medicine Division of Cardiovascular Diseases University of Mississippi Medical Center Jackson MS.
Michael E HallDepartment of Medicine Division of Cardiovascular Diseases University of Mississippi Medical Center Jackson MS.
Naomi M HamburgEvans Department of Medicine Boston University School of Medicine Boston MA.
Emelia J BenjaminBoston University and NHLBI's Framingham Heart Study Framingham MA.
Ramachandran S VasanEvans Department of Medicine Boston University School of Medicine Boston MA.
Gary F MitchellCardiovascular Engineering, Inc Norwood MA.
Ervin R FoxDepartment of Medicine Division of Cardiovascular Diseases University of Mississippi Medical Center Jackson MS.
Jackson Memorial Hospital · USBoston University · USVassar College · USBeth Israel Deaconess Medical Center · USDuke University · USNorwood Hospital · USTougaloo College · US

Funding

IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6M
ConProject-006U54HL120163 · NHLBI · AMERICAN HEART ASSOCIATION · PI BHATNAGAR, ARUNI, ROBERTSON, ROSE MARIE · 2018 to 2022
$18.8M
PRIDE SUMMER INSTITUTE IN CARDIOVASCULAR GENETIC EPIDEMIOLOGYR25HL105400 · NHLBI · WASHINGTON UNIVERSITY · PI DAVILA-ROMAN, VICTOR G., DE LAS FUENTES, LISA · 2010 to 2025
$5.2M
AFGen Consortium: Atrial Fibrillation Genomics to Functional AnalysesR01HL128914 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2015 to 2018
$3.1M
FHS-NEXT - Framingham Novel EXam using TechnologyR01HL141434 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J., MCMANUS, DAVID D. · 2019 to 2022
$2.5M
Renal Sinus Fat, Hypertension, and Altered Kidney FunctionK08DK099415 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI HALL, MICHAEL EDWARD · 2015 to 2019
$791k
Determinants and Prognostic Significance of Proximal Aortic StiffnessK23HL118529 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI TSAO, CONNIE · 2014 to 2018
$742k
NCI NIH HHS HHSN261201800010INCI NIH HHS HHSN261201800012INCI NIH HHS HHSN261201800014INHLBI NIH HHS HHSN268201100011INHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS HHSN268201800015INHLBI NIH HHS K23 HL118529NHLBI NIH HHS R01 HL092577NHLBI NIH HHS R01 HL128914NHLBI NIH HHS R01 HL141434NHLBI NIH HHS R25 HL105400NHLBI NIH HHS U54 HL120163NIDDK NIH HHS K08 DK099415NIMHD NIH HHS HHSN268201800013I
6 · The paper itself

Abstract

Background Measures of vascular dysfunction are related to adverse cardiovascular disease (CVD) outcomes in non-Hispanic, White populations; however, data from Black individuals are limited. We aimed to investigate the associations between novel hemodynamic measures and prevalent CVD in a sample of Black individuals. Methods and Results Among older Black participants of the Jackson Heart Study, we assessed noninvasive vascular hemodynamic measures using arterial tonometry and Doppler ultrasound. We assessed 5 measures of aortic stiffness and wave reflection (carotid-femoral pulse wave velocity, pulse wave velocity ratio, forward pressure wave amplitude, central pulse pressure, and augmentation index), and 2 measures of microvascular function (baseline and hyperemic brachial flow velocity). Using multivariable logistic regression models, we examined the relations between vascular hemodynamic measures and prevalent CVD. In models adjusted for traditional CVD risk factors, higher carotid-femoral pulse wave velocity (odds ratio [OR],1.25; 95% CI, 1.01-1.55;

Indexed as

MicrocirculationVascular StiffnessAgedBlack or African AmericanCardiovascular DiseasesCross-Sectional StudiesFemaleHumansMaleManometryMississippiPrevalencePulse Wave AnalysisRisk Factorsaortic stiffnesscardiovascular diseasemicrovascular functionultrasoundvascular function

Identifiers

PMID32873113
PMCPMC7726980
OpenAlexW3082788993

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.