Evidence map›Paper›PMID 32872758›Full record

ArticleAsian spine journal2021

Relationship between Skeletal Muscle Mass, Bone Mineral Density, and Trabecular Bone Score in Osteoporotic Vertebral Compression Fractures.

Soichiro Tokeshi, Yawara Eguchi, Munetaka Suzuki, Hajime Yamanaka, Hiroshi Tamai, Sumihisa Orita, Kazuhide Inage, Yasuhiro Shiga, Shigeo Hagiwara, Junichi Nakamura and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Asian spine journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Prevalence and risk factors of osteoporosis and fragility fractures in aging Hakka women in Taiwan.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
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  15. Comparison of the efficacy between sequential therapy with teriparatide and denosumab and denosumab monotherapy in suppressing fragility fracture risk.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Soichiro TokeshiDepartment of Orthopaedic Surgery, Shimoshizu National Hospital, Yotsukaido, Japan.
Yawara EguchiDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Munetaka SuzukiDepartment of Orthopaedic Surgery, Shimoshizu National Hospital, Yotsukaido, Japan.
Hajime YamanakaDepartment of Orthopaedic Surgery, Shimoshizu National Hospital, Yotsukaido, Japan.
Hiroshi TamaiDepartment of Orthopaedic Surgery, Shimoshizu National Hospital, Yotsukaido, Japan.
Sumihisa OritaDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Kazuhide InageDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Yasuhiro ShigaDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Shigeo HagiwaraDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Junichi NakamuraDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Tsutomu AkazawaDepartment of Orthopaedic Surgery, St. Marianna University School of Medicine, Kawasaki, Japan.
Hiroshi TakahashiDepartment of Orthopaedic Surgery, Toho University Sakura Medical Center, Sakura, Japan.
Seiji OhtoriDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Chiba University · JPShizuoka City Shimizu Hospital · JPSt. Marianna University School of Medicine · JPToho University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designA retrospective observational study was performed. PURPOSE: We investigated the relationships between skeletal muscle mass, bone mineral density (BMD), and trabecular bone score (TBS) in patients with osteoporotic vertebral compression fractures (VCFs). OVERVIEW OF LITERATURE: The TBS has attracted attention as a measurement of trabecular bone microarchitecture. It is derived from data obtained using dual-energy X-ray absorptiometry (DXA) and is a reported indicator of VCFs, and its addition to the Fracture Risk Assessment Tool increases the accuracy of fracture prediction.

methodsBMD, skeletal muscle mass, and TBS were measured in 142 patients who visited Shimoshizu National Hospital from April to August 2019. Patients were divided into a VCF group and a non-VCF group. Whole-body DXA scans were performed to analyze body composition, including appendicular skeletal muscle mass index (SMI; lean mass [kg]/height [m2]) and BMD. The diagnostic criteria for sarcopenia was an appendicular SMI <5.46 kg/m2. A logistic regression analysis was conducted to identify the risk factors for VCFs.

resultsThe significant (p<0.05) findings (VCF group vs. non-VCF group, respectively) included age (79 vs. 70 years), femoral BMD (0.50 vs. 0.58 g/cm2), TBS (1.25 vs. 1.29), and lower limb muscle mass (8.6 vs. 9.9 kg). The VCF group was significantly older and had a lower femur BMD and decreased leg muscle mass than the non-VCF group. Based on the multiple logistic regression analysis, lower femoral BMD and decreased leg muscle mass were identified as risk factors for vertebral fracture independent of age, but the TBS was not.

conclusionsPatients with VCFs had low BMD, a low TBS, and low skeletal muscle mass. Lower femoral BMD and decreased leg muscle mass were identified as risk factors for VCFs independent of age, whereas the TBS was not identified as a risk factor for VCFs.

Indexed as

Bone densityOsteoporosisSkeletal muscleSpinal fractures

Identifiers

PMID32872758
PMCPMC8217848
OpenAlexW3082878646

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.