ArticleAnimals : an open access journal from MDPI2020
Survey on Sheep Usage in Biomedical Research.
Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Zebrafish as an Integrative Model for Central Nervous System Research: Current Advances and Translational Perspectives.Life (Basel, Switzerland) · 2025Review
- Clinical validation of the Unesp-Botucatu acute pain scale in sheep undergoing orthopedic surgery.PloS one · 2025Article
- Sheep as a large animal model for hearing research: comparison to common laboratory animals and humans.Laboratory animal research · 2023Review
- Donor variability of ovine bone marrow derived mesenchymal stem cell - implications for cell therapy.International journal of veterinary science and medicine · 2023Article
- Large Farm Animals Used for Research Purposes: A Survey on Purchase, Housing and Hygiene Management.Animals : an open access journal from MDPI · 2021Article
- Refinements to Animal Models for Biomedical Research.Animals : an open access journal from MDPI · 2020Article
- Transdermal Fentanyl Uptake at Two Different Patch Locations in Swiss White Alpine Sheep.Animals : an open access journal from MDPI · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Currently, there is a lack of detailed information about sheep used for biomedical research. Therefore, a European survey was conducted among sheep users gathering information on the current situation, with emphasis on animal selection criteria and issues encountered in practice. The ultimate goal was to identify needs for improvement, which will subsequently lead to a refinement and reduction of the total number of animals used for experimental studies. From the 84 respondents, 77.4% were veterinarians, 71.4% were employed at academic institutions and 63.1% had worked with sheep as research animals for more than 5 years. The majority of the respondents were using females (79.8%) with no clear age preference, mainly for surgical procedures and testing medical devices. The main criteria for choosing a sheep supplier were the animals' health status, their availability, the trust and experience in the sheep provider and the animals' uniformity. Approximately 60% of the respondents had encountered problems in their sheep not related to the experimental protocol and almost half of them did not have a health monitoring program for their animals. In conclusion, there is definitely a need for refinement in selecting sheep used in biomedical research, with their health status as possible starting point.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.