Evidence map›Paper›PMID 32872526›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Beyond Uterine Natural Killer Cell Numbers in Unexplained Recurrent Pregnancy Loss: Combined Analysis of CD45, CD56, CD16, CD57, and CD138.

Maia Chiokadze, Christin Bär, Jana Pastuschek, Boris V Dons'koi, Kseniia G Khazhylenko, Ekkehard Schleußner, Udo R Markert, Rodolfo R Favaro

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Role of CD138Biomedicines · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Maia ChiokadzePlacenta Lab, Department of Obstetrics, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0002-1339-0832
Christin BärPlacenta Lab, Department of Obstetrics, Jena University Hospital, 07747 Jena, Germany.
Jana PastuschekPlacenta Lab, Department of Obstetrics, Jena University Hospital, 07747 Jena, Germany.
Boris V Dons'koiLaboratory of Immunology, Institute of Pediatrics, Obstetrics and Gynecology, National Academy of Medical Sciences of Ukraine, 04050 Kyiv, Ukraine.
Kseniia G KhazhylenkoReproductive Medicine Clinic Isida, 02000 Kyiv, Ukraine.
Ekkehard SchleußnerPlacenta Lab, Department of Obstetrics, Jena University Hospital, 07747 Jena, Germany.
Udo R MarkertPlacenta Lab, Department of Obstetrics, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0001-5299-595X
Rodolfo R FavaroPlacenta Lab, Department of Obstetrics, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0002-2889-5921
Jena University Hospital · DEKyiv City Clinical Oncology Center · UANational Academy of Medical Sciences of Ukraine · UAReproductive Science Center · US

Funding

Deutscher Akademischer Austauschdienst Rustaveli-DAAD-Fellowship Programme, no. 91677531
6 · The paper itself

Abstract

Changes in the number and cytotoxic potential of uterine Natural Killer (uNK) cells have been associated with reduced fertility. To provide a better characterization of immunophenotypes in the endometrium of women with uRPL (unexplained recurrent pregnancy loss), we examined the applicability of a set of five immune cell markers. The concentration (cells/mm

Indexed as

CD138CD16CD45CD56CD57endometriumhumannatural killer cellsrecurrent pregnancy loss

Identifiers

PMID32872526
PMCPMC7555015
OpenAlexW3082110650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.