Evidence map›Paper›PMID 32872355›Full record

ReviewPharmaceuticals (Basel, Switzerland)2020

Towards Better Delivery of Cannabidiol (CBD).

Sophie Anne Millar, Ryan Francis Maguire, Andrew Stephen Yates, Saoirse Elizabeth O'Sullivan

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Use of Cannabidiol in Cutaneous Wound Healing: A Systematic Review.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Development andDrug delivery · 2026
    Article
  6. Reimagining Cannabidiol Delivery Through Carbon Nanodots.Molecules (Basel, Switzerland) · 2026
    Review
  7. Review
  8. GABACellular and molecular neurobiology · 2026
    Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Cannabidiol: Pharmaceutical formulations and biomedical applications.Iranian journal of basic medical sciences · 2026
    Review
  15. ComparativeFrontiers in toxicology · 2026
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article

46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sophie Anne MillarArtelo Biosciences, 888 Prospect Street, Suite 210, La Jolla, CA 92037, USA.
Ryan Francis MaguireDivision of Graduate Entry Medicine and Medical Sciences, School of Medicine, University of Nottingham, Royal Derby Hospital, Derby DE22 3DT, UK.
Andrew Stephen YatesArtelo Biosciences, 888 Prospect Street, Suite 210, La Jolla, CA 92037, USA.
Saoirse Elizabeth O'SullivanArtelo Biosciences, 888 Prospect Street, Suite 210, La Jolla, CA 92037, USA.ORCID 0000-0002-1672-6610

Funding

Artelo Biosciences n/a
6 · The paper itself

Abstract

Cannabidiol (CBD) has substantial therapeutic potential, but its development as an effective drug by the pharmaceutical industry is hindered by intrinsic characteristics such as low bioavailability, low water solubility, and variable pharmacokinetic profiles. Importantly, lack of patentability of the drug substance also limits the likelihood of an expensive, full development programme in anything other than orphan indications. Potential avenues to overcome these issues with CBD include self-emulsifying drug delivery systems, improved crystal formulations and other solid-state delivery formulations, which are mostly in the pre-clinical or early clinical stages of development. This review identifies issues compromising current delivery of solid-state CBD, and how advanced pharmaceutical development strategies can enable CBD to realise the full potential as a successful therapeutic agent.

Indexed as

cannabidiolCBDclinical developmentformulation

Identifiers

PMID32872355
PMCPMC7558665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.