Evidence map›Paper›PMID 32872351›Full record

ArticleCells2020

Endothelial Dysfunction Following Enhanced TMEM16A Activity in Human Pulmonary Arteries.

Davor Skofic Maurer, Diana Zabini, Chandran Nagaraj, Neha Sharma, Miklós Lengyel, Bence M Nagy, Saša Frank, Walter Klepetko, Elisabeth Gschwandtner, Péter Enyedi and 3 more

Abstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Lipid Ratios for Diagnosis and Prognosis of Pulmonary Hypertension.American journal of respiratory and critical care medicine · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. CaInternational journal of molecular sciences · 2024
    Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Davor Skofic MaurerOtto Loewi Research Center, Medical University of Graz, Neue Stiftingtalstraße 6, 8010 Graz, Austria.
Diana ZabiniOtto Loewi Research Center, Medical University of Graz, Neue Stiftingtalstraße 6, 8010 Graz, Austria.
Chandran NagarajLudwig Boltzmann Institute for Lung Vascular Research, Neue Stiftingtalstraße 6, 8010 Graz, Austria.
Neha SharmaExperimental Anaesthesiology, Department of Anaesthesiology and Intensive Care Medicine, Medical University of Graz, Auenbruggerplatz 5, 8036 Graz, Austria.
Miklós LengyelDepartment of Physiology, Semmelweis University, Tűzoltó utca 37-47, 1094 Budapest, Hungary.ORCID 0000-0001-6382-6369
Bence M NagyLudwig Boltzmann Institute for Lung Vascular Research, Neue Stiftingtalstraße 6, 8010 Graz, Austria.ORCID 0000-0003-3955-4863
Saša FrankGottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6, 8010 Graz, Austria.
Walter KlepetkoDepartment of Thoracic Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.
Elisabeth GschwandtnerDepartment of Thoracic Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.ORCID 0000-0002-0618-7342
Péter EnyediDepartment of Physiology, Semmelweis University, Tűzoltó utca 37-47, 1094 Budapest, Hungary.
Grazyna KwapiszewskaOtto Loewi Research Center, Medical University of Graz, Neue Stiftingtalstraße 6, 8010 Graz, Austria.
Horst OlschewskiLudwig Boltzmann Institute for Lung Vascular Research, Neue Stiftingtalstraße 6, 8010 Graz, Austria.
Andrea OlschewskiLudwig Boltzmann Institute for Lung Vascular Research, Neue Stiftingtalstraße 6, 8010 Graz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial dysfunction is one of the hallmarks of different vascular diseases, including pulmonary arterial hypertension (PAH). Ion channelome changes have long been connected to vascular remodeling in PAH, yet only recently has the focus shifted towards Ca

Indexed as

Anoctamin-1Endothelial CellsHumansNeoplasm ProteinsPulmonary ArteryANO1 protein, humanAnoctamin-1Neoplasm ProteinsangiogenesisAno1benzbromaroneendothelial dysfunctioneNOS uncouplingintracellular calciummetabolic switchpulmonary endothelial cellspulmonary hypertensionTMEM16A

Identifiers

PMID32872351
PMCPMC7563136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.