Evidence map›Paper›PMID 32872305›Full record

ArticleInternational journal of molecular sciences2020

Role of Poly [ADP-ribose] Polymerase 1 in Activating the

Giorgio Cinque, Annalisa Ferino, Erik B Pedersen, Luigi E Xodo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Crosstalk between G-quadruplex and ROS.Cell death & disease · 2023
    Review
  7. Article
  8. hnRNPA1/UP1 UnfoldsACS omega · 2021
    Article
  9. G-quadruplex DNA: a novel target for drug design.Cellular and molecular life sciences : CMLS · 2021
    Review
  10. Review
  11. Effect of DNA Glycosylases OGG1 and Neil1 on Oxidized G-Rich Motif in theInternational journal of molecular sciences · 2021
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Giorgio CinqueDepartment of Medicine, Laboratory of Biochemistry, P.le Kolbe 4, 33100 Udine, Italy.
Annalisa FerinoDepartment of Medicine, Laboratory of Biochemistry, P.le Kolbe 4, 33100 Udine, Italy.
Erik B PedersenNucleic Acid Center, Institute of Physics and Chemistry, University of Southern Denmark, DK-5230 Odense, Denmark.
Luigi E XodoDepartment of Medicine, Laboratory of Biochemistry, P.le Kolbe 4, 33100 Udine, Italy.ORCID 0000-0003-3344-7207
University of Udine · ITUniversity of Southern Denmark · DK

Funding

Associazione Italiana per la Ricerca sul Cancro IG 2017, Project code 19898
6 · The paper itself

Abstract

In pancreatic Panc-1 cancer cells, an increase of oxidative stress enhances the level of 7,8-dihydro-8-oxoguanine (8OG) more in the

Indexed as

Up-RegulationBenzimidazolesCell Line, TumorDNA-Binding ProteinsGene Expression Regulation, NeoplasticGene SilencingG-QuadruplexesGuanineHeterogeneous Nuclear Ribonucleoprotein A1HumansHydrogen PeroxideOxidative StressPancreatic NeoplasmsPoly (ADP-Ribose) Polymerase-1Promoter Regions, GeneticProto-Oncogene Proteins p21(ras)7,8-dihydro-8-oxoguanineBenzimidazolesc-MYC-associated zinc finger proteinDNA-Binding ProteinsGuanineHeterogeneous Nuclear Ribonucleoprotein A1Hydrogen PeroxideKRAS protein, humanPARP1 protein, humanPoly (ADP-Ribose) Polymerase-1Proto-Oncogene Proteins p21(ras)Transcription Factorsveliparib8-oxoguanineG4 DNAKRASoxidative stressPARP-1transcription factorstranscription regulation

Identifiers

PMID32872305
PMCPMC7504130
OpenAlexW3082249859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.