Evidence map›Paper›PMID 32872283›Full record

ArticleViruses2020

Evaluation of the 50% Infectious Dose of Human Norovirus Cin-2 in Gnotobiotic Pigs: A Comparison of Classical and Contemporary Methods for Endpoint Estimation.

Ashwin K Ramesh, Viviana Parreño, Philip J Schmidt, Shaohua Lei, Weiming Zhong, Xi Jiang, Monica B Emelko, Lijuan Yuan

Open access · goldAbstract readComparative Study
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Ashwin K RameshDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24060, USA.ORCID 0000-0002-4009-6823
Viviana ParreñoInstituto de Virología, Instituto Nacional de Tecnología Agropecuaria (INTA), Castelar 1712, Argentina.
Philip J SchmidtWater Science, Technology & Policy Group, Department of Civil & Environmental Engineering, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
Shaohua LeiDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24060, USA.ORCID 0000-0001-7332-6827
Weiming ZhongDivision of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Xi JiangDivision of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Monica B EmelkoWater Science, Technology & Policy Group, Department of Civil & Environmental Engineering, University of Waterloo, Waterloo, ON N2L 3G1, Canada.ORCID 0000-0002-8295-0071
Lijuan YuanDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24060, USA.ORCID 0000-0003-0709-5228
Virginia–Maryland College of Veterinary Medicine · USCincinnati Children's Hospital Medical Center · USUniversity of Waterloo · CANational Institute of Industrial Technology · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human noroviruses (HuNoVs) are the leading causative agents of epidemic and sporadic acute gastroenteritis that affect people of all ages worldwide. However, very few dose-response studies have been carried out to determine the median infectious dose of HuNoVs. In this study, we evaluated the median infectious dose (ID

Indexed as

AnimalsCaliciviridae InfectionsDisease Models, AnimalFemaleGastroenteritisGerm-Free LifeHumansMaleNorovirusSwineVirologyVirulenceapproximate beta-Poissondose–responsemedian infectious doseReed–MuenchSpearman–Karber

Identifiers

PMID32872283
PMCPMC7552045
OpenAlexW3081837101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.