Evidence map›Paper›PMID 32872205›Full record

ReviewBiomolecules2020

Computational Methods and Software Tools for Functional Analysis of miRNA Data.

Adrian Garcia-Moreno, Pedro Carmona-Saez

Abstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Hepatitis B Virus and microRNAs: A Bioinformatics Approach.International journal of molecular sciences · 2023
    Review
  10. Review
  11. Article
  12. Milking miRNAs for All Their Worth.The Journal of nutrition · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adrian Garcia-MorenoBioinformatics Unit, Centre for Genomics and Oncological Research (GENyO)-Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, 18016 Granada, Spain.ORCID 0000-0002-5715-4962
Pedro Carmona-SaezBioinformatics Unit, Centre for Genomics and Oncological Research (GENyO)-Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, 18016 Granada, Spain.ORCID 0000-0002-6173-7255

Funding

Junta de Andalucía PI-0173-2017
6 · The paper itself

Abstract

miRNAs are important regulators of gene expression that play a key role in many biological processes. High-throughput techniques allow researchers to discover and characterize large sets of miRNAs, and enrichment analysis tools are becoming increasingly important in decoding which miRNAs are implicated in biological processes. Enrichment analysis of miRNA targets is the standard technique for functional analysis, but this approach carries limitations and bias; alternatives are currently being proposed, based on direct and curated annotations. In this review, we describe the two workflows of miRNAs enrichment analysis, based on target gene or miRNA annotations, highlighting statistical tests, software tools, up-to-date databases, and functional annotations resources in the study of metazoan miRNAs.

Indexed as

SoftwareAnimalsComputational BiologyDatabases, GeneticData Interpretation, StatisticalHumansMicroRNAsMolecular Sequence AnnotationMicroRNAsdatabasesenrichmentfunctional analysismiRNAncRNAtools

Identifiers

PMID32872205
PMCPMC7563698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.