Evidence map›Paper›PMID 32872147›Full record

ReviewCancers2020

Epstein-Barr Virus Mediated Signaling in Nasopharyngeal Carcinoma Carcinogenesis.

Timmy Richardo, Pongphol Prattapong, Chawalit Ngernsombat, Nurulfitri Wisetyaningsih, Hisashi Iizasa, Hironori Yoshiyama, Tavan Janvilisri

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Integrating multi-omics data for next-generation cancer research and precision medicine.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Timmy RichardoInstitute of Virology, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-4927-2715
Pongphol PrattapongGraduate Program in Molecular Medicine, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Chawalit NgernsombatGraduate Program in Molecular Medicine, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Nurulfitri WisetyaningsihDepartment of Biomedicine, Indonesia International Institute for Life Science (i3L), Jakarta 13210, Indonesia.ORCID 0000-0002-6790-152X
Hisashi IizasaDepartment of Microbiology, Shimane University, Izumo 693-8501, Japan.ORCID 0000-0002-9202-2666
Hironori YoshiyamaDepartment of Microbiology, Shimane University, Izumo 693-8501, Japan.ORCID 0000-0001-7588-278X
Tavan JanvilisriDepartment of Biochemistry, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.ORCID 0000-0002-6376-5575
Mahidol University · THShimane University · JPIndonesia International Institute for Life Sciences · ID

Funding

Thailand Research Fund BRG5980003
6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) is one of the most common tumors occurring in China and Southeast Asia. Etiology of NPC seems to be complex and involves many determinants, one of which is Epstein-Barr virus (EBV) infection. Although evidence demonstrates that EBV infection plays a key role in NPC carcinogenesis, the exact relationship between EBV and dysregulation of signaling pathways in NPC needs to be clarified. This review focuses on the interplay between EBV and NPC cells and the corresponding signaling pathways, which are modulated by EBV oncoproteins and non-coding RNAs. These altered signaling pathways could be critical for the initiation and progression of NPC.

Indexed as

EBVinfectionnasopharyngeal carcinomaoncogenesissignaling pathway

Identifiers

PMID32872147
PMCPMC7565514
OpenAlexW3082934977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.