ArticleNutrients2020
Association of Weight Loss from Early to Middle Adulthood and Incident Hypertension Risk Later in Life.
Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Life stage-specific heterogeneity in the effects of adiposity transition on hypertension incidence and resolution.International journal of obesity (2005) · 2026Article
- Long-term weight change patterns in American adulthood in relation to gallstones: evidence from NHANES.BMC gastroenterology · 2025Article
- The associations between healthy lifestyle scores, their long-term changes, and incident hypertension risk in adults: a prospective cohort study.Frontiers in cardiovascular medicine · 2025Article
- Weight changes from early to middle adulthood and cardiometabolic multimorbidity later in life among middle-aged and older adults: a retrospective cohort study from the NHANES 1999-2018.Frontiers in endocrinology · 2024Article
- Relationship of weight change patterns from young to middle adulthood with incident rheumatoid arthritis and osteoarthritis: a retrospective cohort study.Frontiers in endocrinology · 2023Article
- Weight Change across Adulthood in Relation to Non-Alcoholic Fatty Liver Disease among Non-Obese Individuals.Nutrients · 2022Article
- Association between age at onset of overweight and risk of hypertension across adulthood.Heart (British Cardiac Society) · 2022Article
- Weight gain from early to middle adulthood increases the risk of incident asthma later in life in the United States: a retrospective cohort study.Respiratory research · 2021Article
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundThe effect of obesity in early adulthood and weight loss on incident hypertension in older age has not been well characterized. This study aimed to examine the association of weight loss from young adulthood to midlife with risk of incident hypertension later in life.
methodsWe performed a retrospective cohort study using data from the National Health and Nutrition Examination Survey (NHANES). Five weight change groups were categorized: stable normal, weight loss, weight gain, maximum overweight and stable obese. The hazard ratios (HRs) and 95% confidence intervals (CIs) of the association between weight change and risk of hypertension in later life were estimated using Cox regression models.
resultsCompared with participants who maintained normal weight, the stable obese, weight gain, maximum overweight and weight loss groups exhibited significantly higher risks of incident hypertension, with HR of 3.28 (95% CI = 2.71 to 3.96), 2.93 (95% CI = 2.62 to 3.28), 1.76 (95% CI = 1.55 to 2.00) and 1.97 (95% CI = 1.17 to 3.31), respectively. We also observed a lower risk among those in the weight loss group (HR = 0.60, 95% CI = 0.35 to 1.02) compared with those who were stable obese.
conclusionsWeight loss from early to middle adulthood was associated with lower risk of incident hypertension as compared to those who stayed obese and higher risk of incident hypertension as compared to those who maintained normal weight. Thus, maintaining normal weight throughout adulthood may be important for the primary prevention of hypertension.
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