Evidence map›Paper›PMID 32872042›Full record

Observational studyMedicine2020

Relationship between chemotherapy-induced adverse reactions and health-related quality of life in patients with breast cancer.

Blanca Prieto-Callejero, Francisco Rivera, Javier Fagundo-Rivera, Adolfo Romero, Macarena Romero-Martín, Juan Gómez-Salgado, Carlos Ruiz-Frutos

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 6 pooled it
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 6 syntheses or guidelines pooled it, 100 citations in OpenAlex.

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  8. A latent profile analysis of patient activation in postoperative breast cancer patients: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  20. ThePharmaceuticals (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Blanca Prieto-CallejeroHospital Virgen de la Bella, Lepe, Huelva.
Francisco RiveraDepartment of Experimental Psychology, Faculty of Psychology, University of Seville, Seville.
Javier Fagundo-RiveraDepartment of Health and Emergencies, Spanish Red Cross, Local Committee of Seville, Doctoral Programme, University of Huelva, Huelva.
Adolfo RomeroUniversity Hospital Virgen de la Victoria, Nursing and Podiatry Department, Health Sciences School, University of Málaga, Málaga.
Macarena Romero-MartínNursing Department, Faculty of Nursing, University of Huelva.
Juan Gómez-SalgadoPreventive Medicine and Public Health Unit, Sociology, Social Work and Public Health Department, Labour Sciences Faculty, University of Huelva, Huelva, Spain.
Carlos Ruiz-FrutosPreventive Medicine and Public Health Unit, Sociology, Social Work and Public Health Department, Labour Sciences Faculty, University of Huelva, Huelva, Spain.
Universidad de Huelva · ESUniversidad de Especialidades Espíritu Santo · ECUniversidad de Málaga · ESUniversidad de Sevilla · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesChemotherapy does not only affect cancer cells; it also affects, to a greater or lesser degree, all other cells in the body. This toxicity should be assessed according to its severity, frequency, and duration, taking into account objective and subjective dimensions in its assessment. This assessment is a highly relevant aspect when providing care to chemotherapy patients, mainly due to the impact of the treatment on the patient's quality of life, as well as the vital risk it may imply under certain circumstances. For all this, the objective of this study was to assess the relationship between chemotherapy-associated adverse reactions and health-related quality of life in breast cancer patients. MATERIALS AND

methodsWith this purpose, a descriptive cross-sectional study was developed on 110 breast cancer patients who were treated with docetaxel, epirubicin, and cyclophosphamide.

resultsIt is worth highlighting the negative effect of nausea, dysgeusia, peripheral neuropathy, loss of appetite, myalgia, and peripheral edema on the quality of life. Likewise, it is worth mentioning peripheral neuropathy as the toxicity that affects a greater number of quality-of-life indicators.

conclusionsTo sum up, it would be necessary to make health professionals aware of the importance of chemotherapy-associated adverse reactions.

Indexed as

Quality of LifeActivities of Daily LivingAdultAgedAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsBreast NeoplasmsCross-Sectional StudiesFemaleHumansMiddle AgedSurveys and QuestionnairesAntineoplastic Agents

Identifiers

PMID32872042
PMCPMC7437745
OpenAlexW3049652479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.