Evidence map›Paper›PMID 32871999›Full record

ArticleMedicine2020

Human coronavirus OC43 infection associated pneumonia in a girl with acute lymphoblastic leukemia: A case report.

Tsung-Yen Chang, Chia-Jui Du, Chih-Chen Chang, Shih-Hsiang Chen, Chih-Jung Chen, Chih-Yung Chiu, Cheng-Hsun Chiu

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Tsung-Yen ChangDivision of Pediatric Hematology-Oncology.
Chia-Jui DuDivision of Pediatric General Medicine.
Chih-Chen ChangDepartment of Medical Imaging and Intervention.
Shih-Hsiang ChenDivision of Pediatric Hematology-Oncology.ORCID 0000-0003-2588-2735
Chih-Jung ChenDivision of Pediatric Infectious Diseases.
Chih-Yung ChiuDivision of Pediatric Pulmonology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Cheng-Hsun ChiuDivision of Pediatric Infectious Diseases.
Chang Gung University · TWS.P.E.C.I.E.S. · USGeneral Department of Preventive Medicine · VNPediatric Infectious Diseases Society · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleInformation regarding the clinical features and outcomes of pneumonia due to an infection with human coronavirus (HCoV)-OC43 in children with cancer is rare. This report presents the clinical features in terms of chest CT scan images which may be used to identify cases of HCoV-OC43 infection induced pneumonia in immunocompromised children. PATIENT CONCERNS: We report here a girl with acute lymphoblastic leukemia who developed respiratory symptoms during febrile neutropenia. Rapid clinical progression and nodular lesions on her chest X-ray and computed tomography scans were suggestive of a pulmonary fungal infection. DIAGNOSIS: A series of tests eventually confirmed the exclusive presence of HCoV-OC43 by the FilmArray Respiratory Panel from a throat swab sample.

interventionsAfter the diagnosis was confirmed, the antimicrobial agents initially administered were discontinued. OUTCOMES: Although the chest CT scan images looked severe, the clinical course of the infection induced pneumonia was benign. The respiratory status of the patient was completely resolved in 2 weeks. LESSONS: This report highlights the importance of early identification of respiratory viruses, via the realization of their clinical characteristics, which helps reduce the duration of administration of antimicrobial agents in this setting.

Indexed as

ChildCoronavirus InfectionsCoronavirus OC43, HumanFebrile NeutropeniaFemaleHumansImmunocompromised HostPneumonia, ViralPolymerase Chain ReactionPrecursor Cell Lymphoblastic Leukemia-Lymphoma

Identifiers

PMID32871999
PMCPMC7437800
OpenAlexW3049643695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.