Evidence map›Paper›PMID 32871964›Full record

ArticleMedicine2020

Prognostic value of serum albumin-to-creatinine ratio in patients with acute myocardial infarction: Results from the retrospective evaluation of acute chest pain study.

Hong Liu, Jianna Zhang, Jing Yu, Dongze Li, Yu Jia, Yisong Cheng, Qin Zhang, Xiaoyang Liao, Yanmei Liu, Jiang Wu and 5 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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  17. Diagnostic and Prognostic Biomarkers for Myocardial Infarction.Frontiers in cardiovascular medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Hong LiuDepartment of Emergency Medicine, Laboratory of Emergency Medicine, Deep Underground Space Medical Center, West China School of Nursing, West China Hospital, and Disaster Medical Center, Sichuan University, Chengdu, China.ORCID 0000-0002-6666-0082
Jianna ZhangDepartment of Emergency Medicine, Laboratory of Emergency Medicine, Deep Underground Space Medical Center, West China School of Nursing, West China Hospital, and Disaster Medical Center, Sichuan University, Chengdu, China.
Jing YuWest China School of Nursing, West China Hospital, Sichuan University, Chengdu, China.
Dongze LiDepartment of Emergency Medicine, Laboratory of Emergency Medicine, Deep Underground Space Medical Center, West China School of Nursing, West China Hospital, and Disaster Medical Center, Sichuan University, Chengdu, China.
Yu JiaDepartment of Emergency Medicine, Laboratory of Emergency Medicine, Deep Underground Space Medical Center, West China School of Nursing, West China Hospital, and Disaster Medical Center, Sichuan University, Chengdu, China.
Yisong ChengDepartment of Emergency Medicine, Laboratory of Emergency Medicine, Deep Underground Space Medical Center, West China School of Nursing, West China Hospital, and Disaster Medical Center, Sichuan University, Chengdu, China.
Qin ZhangDepartment of Emergency Medicine, Laboratory of Emergency Medicine, Deep Underground Space Medical Center, West China School of Nursing, West China Hospital, and Disaster Medical Center, Sichuan University, Chengdu, China.
Xiaoyang LiaoDepartment of General Practice, International Hospital of Sichuan Province, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China.
Yanmei LiuChinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu, China.
Jiang WuDepartment of Emergency Medicine, Laboratory of Emergency Medicine, Deep Underground Space Medical Center, West China School of Nursing, West China Hospital, and Disaster Medical Center, Sichuan University, Chengdu, China.
Zhi ZengDepartment of Emergency Medicine, Laboratory of Emergency Medicine, Deep Underground Space Medical Center, West China School of Nursing, West China Hospital, and Disaster Medical Center, Sichuan University, Chengdu, China.
Yu CaoDepartment of Emergency Medicine, Laboratory of Emergency Medicine, Deep Underground Space Medical Center, West China School of Nursing, West China Hospital, and Disaster Medical Center, Sichuan University, Chengdu, China.
Rui ZengDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, China.
Zhi WanDepartment of Emergency Medicine, Laboratory of Emergency Medicine, Deep Underground Space Medical Center, West China School of Nursing, West China Hospital, and Disaster Medical Center, Sichuan University, Chengdu, China.
Yongli GaoDepartment of Emergency Medicine, Laboratory of Emergency Medicine, Deep Underground Space Medical Center, West China School of Nursing, West China Hospital, and Disaster Medical Center, Sichuan University, Chengdu, China.
West China Medical Center of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The long-term association between serum albumin-to-creatinine ratio (sACR) and poor patient outcomes in acute myocardial infarction (AMI) remains unclear. This study aimed to determine whether sACR was a predictor of poor long-term survival in patients with AMI.This was a study of patients with AMI in the emergency department (ED) from the retrospective multicenter study for early evaluation of acute chest pain (REACP) study. The patients were categorized into tertiles (T1, T2, and T3) based on the admission sACR (0.445 and 0.584 g/μmol). Baseline sACR at admission to the ED was predictive of adverse outcomes. The primary outcome was all-cause mortality within the follow-up period. Cox proportional hazards models were performed to investigate the association between sACR and all-cause mortality in patients with AMI.A total of 2250 patients with AMI were enrolled, of whom 229 (10.2%) died within the median follow-up period of 10.7 (7.2-14.6) months. Patients with a lower sACR had higher all-cause mortality and adverse outcomes rates than patients with a higher sACR. Kaplan-Meier survival analysis showed that patients with a higher sACR had a higher cumulative survival rate (P < .001). Cox regression analysis showed that a decreased sACR was an independent predictor of all-cause mortality [T2 vs T1: hazard ratio (HR); 0.550, 95% confidence interval (95% CI), 0.348-0.867; P = .010 and T3 vs T1: HR, 0.305; 95% CI, 0.165-0.561; P < .001] and cardiac mortality (T2 vs T1: HR, 0.536; 95% CI, 0.332-0.866; P = .011 and T3 vs T1: HR, 0.309; 95% CI, 0.164-0.582, P < .001).The sACR at admission to ED was independently associated with adverse outcomes, indicating that baseline sACR was a useful biomarker to identify high-risk patients with AMI at an early phase in ED.

Indexed as

AgedAged, 80 and overBiomarkersChinaCreatinineFemaleHumansMaleMiddle AgedMyocardial InfarctionRetrospective StudiesSerum AlbuminBiomarkersCreatinineSerum Albumin

Identifiers

PMID32871964
PMCPMC7458165
OpenAlexW3080659655

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.