ArticleMedicine2020
The efficacy and safety of acupuncture or combined with western medicine for dry eye: A protocol for systematic review and meta-analysis.
Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Role of Chinese Medicine Monomers in Dry Eye Disease: Breaking the Vicious Cycle of Inflammation.Pharmacology research & perspectives · 2025Review
- Tolerability of Current Treatments for Dry Eye Disease: A Review of Approved and Investigational Therapies.Clinical ophthalmology (Auckland, N.Z.) · 2024Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs a traditional Chinese medicine external treatment method, acupuncture is characterized by simple operation, significant treatment effect and few side effects. Dry eye, also known as conjunctival xerosis, refers to pathological changes in tissues of ocular surface caused by abnormal tear quality and quantity or dynamics due to various reasons, which can cause red and swollen eyes, congestion, and severe cases may result in lesions of the conjunctiva. Clinical practice shows that acupuncture has a certain therapeutic effect on dry eye, but there is a lack of medical evidence. The objective of the research carried out in this program is to evaluate the effectiveness and safety of acupuncture combined with western medicine in the treatment of dry eye.
methodsComputer retrieval English database (PubMed, Embase, Web of Science, the Cochrane Library) and Chinese database (CNKI, WF, VIP, CBMDISC), moreover manual retrieval of clinical research on the treatment of dry eyes by acupuncture in combination with western medicine from Baidu academic and Google Academic from database building to May 2020, the quality included in the study was evaluated and data extraction was completed by 2 independent researchers. RevMan5.3 software was utilized for meta-analysis to the included literature.
resultsIn this study, the effectiveness and safety of acupuncture combined with western medicine in the treatment of dry eye were evaluated by several indicators, such as the score of the ocular surface disease index, the amount of tear secretion and the tear film rupture time.
conclusionsThis study will provide reliable evidence for the clinical application of acupuncture combined with western medicine in the treatment of dry eyes. OSF REGISTRATION NUMBER: DOI 10.17605/OSF.IO/5DJ9W.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.