Evidence map›Paper›PMID 32871813›Full record

ArticleIn vivo (Athens, Greece)

Comparison of Three Fractionation Schedules in Radiotherapy for Early Glottic Squamous Cell Carcinoma.

Gen Suzuki, Hideya Yamazaki, Norihiro Aibe, Koji Masui, Daisuke Shimizu, Takuya Kimoto, Takeshi Nishimura, Kanako Kawabata, Shinsuke Nagasawa, Kazutaka Machida and 6 more

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Oncological outcome of vocal cord-only radiotherapy for cT1-T2 glottic laryngeal squamous cell carcinoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
  4. The outcome of early-stage glottic carcinoma patients treated with radiotherapy: Egyptian National Cancer Institute (NCI-Egypt) experience.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Gen SuzukiDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan gensuzu@koto.kpu-m.ac.jp.
Hideya YamazakiDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Norihiro AibeDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Koji MasuiDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Daisuke ShimizuDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Takuya KimotoDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Takeshi NishimuraDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Kanako KawabataDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Shinsuke NagasawaDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Kazutaka MachidaDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Yuki YoshinoDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Sho WatanabeDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Yoichiro SugiyamaDepartment of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Akihito AraiDepartment of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Shigeru HiranoDepartment of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Kei YamadaDepartment of Radiology, Kyoto Prefectural University Graduate School of Medical Science, Kyoto, Japan.
Kyoto Prefectural University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimRadiotherapy is widely accepted as the treatment of choice for early glottic squamous cell carcinoma (EGSCC), although it varies greatly with respect to dose, dose per fraction, and treatment techniques. The study aim was to evaluate the use of accelerated fractionation strategy (AFS) for EGSCC in standard clinical practice. PATIENTS AND

methodsPatients treated with definitive radiotherapy for EGSCC between 2008 and 2019 were retrospectively identified and received either conventional fractionation, hypofractionation, or hyperfractionation.

resultsOne hundred six patients were analyzed, and 19, 71, and 16 patients underwent conventional fractionation, hypofractionation, and hyperfractionation, respectively. The median follow-up was 56 months. The 5-year local control and overall survival rates were 79% and 83%; 78% and 79%; and 87% and 77%, respectively, and no significant difference was observed between the fractionation schedules.

conclusionOur findings confirmed the utility of AFS in standard clinical practice and support its use for patients with EGSCC.

Indexed as

Carcinoma, Squamous CellGlottisHead and Neck NeoplasmsDose Fractionation, RadiationHumansRadiotherapy DosageRetrospective Studiesaltered fractionationGlottic cancerhyperfractionationhypofractionationlate-course accelerated hyperfractionationradiation

Identifiers

PMID32871813
PMCPMC7652429
OpenAlexW3082121941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.