Evidence map›Paper›PMID 32871801›Full record

ArticleIn vivo (Athens, Greece)

Preliminary Report: Asymmetric Crypt Fission in Biopsies from Patients With Ulcerative Colitis.

Carlos A Rubio, Peter T Schmidt

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Carlos A RubioGastrointestinal and Liver Research Laboratory, Department of Pathology, Karolinska Institute and University Hospital, Centre for Digestive Diseases, Stockholm, Sweden Carlos.Rubio@ki.se.
Peter T SchmidtDepartment of Medicine, Karolinska Institute and University Hospital, Centre for Digestive Diseases, Stockholm, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecently, we found crypts with asymmetric fission bordering ulcers in colectomy specimens from patients with ulcerative colitis (UC). Here, we report crypts with asymmetric fission found in biopsies from patients with UC. PATIENTS AND

methodsSections from endoscopic biopsies from five patients with UC were reviewed. The number of transected (cut-across) crypts in symmetric and asymmetric fission was assessed in sections from three biopsies in each patient.

resultsA total of 89 crypts in fission were recorded in the 15 biopsies; 36 (40.4%) were in symmetric fission and the remaining 53 (59.6%) in asymmetric fission.

conclusionA high frequency of asymmetric crypts in fission was demonstrated in endoscopic biopsies from patients with UC. It is suggested that this previously unaddressed histological parameter is included in pathological descriptions of endoscopic biopsies from patients with UC.

Indexed as

Colitis, UlcerativeBiopsyColonHumansIntestinal MucosaUlcerasymmetric fissionColoncrypt fissionmorphology

Identifiers

PMID32871801
PMCPMC7652456
OpenAlexW3082680244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.