Evidence map›Paper›PMID 32871788›Full record

ArticleIn vivo (Athens, Greece)

Intensity-modulated Radiation Therapy for Lymph Node Oligo-recurrence.

Akiko Sato, Motoko Omura, Yumiko Minagawa, Kengo Matsui, Ryosuke Shirata, Hideyuki Hongo, Harumitsu Hashimoto, Toshihiro Misumi, Tomio Inoue, Masaharu Hata

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Akiko SatoDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan akikosato.tk@gmail.com.
Motoko OmuraDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.
Yumiko MinagawaDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.
Kengo MatsuiDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.
Ryosuke ShirataDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.
Hideyuki HongoDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.
Harumitsu HashimotoDepartment of Radiation Oncology, Shonan Fujisawa Tokushukai Hospital, Fujisawa, Japan.
Toshihiro MisumiDepartment of Biostatistics, Yokohama City University School of Medicine, Yokohama, Japan.
Tomio InoueDepartment of Advanced Medical Center, Shonan Kamakura General Hospital, Kamakura, Japan.
Masaharu HataDepartment of Radiation Oncology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThis study aimed to evaluate the effect of intensity-modulated radiation therapy (IMRT) on the clinical outcomes of patients with lymph node (LN) oligo-recurrence and a controlled primary tumor. PATIENTS AND

methodsWe retrospectively reviewed the medical records of 21 patients diagnosed with LN oligo-recurrence who received IMRT with curative intent. Patients with tumor of various primary sites and histopathological types were included in this study.

resultsThe 3-year overall survival (OS) and in-field progression-free survival (PFS) rates were 75% and 52%, respectively. Statistical analysis showed that lower dose to the gross tumor volume (GTV) and larger GTV were significantly associated with poorer OS; adenocarcinoma and lower dose to GTV were significantly associated with poorer in-field PFS. No patients experienced severe adverse events.

conclusionIMRT may provide a safe and effective treatment for patients with LN oligo-recurrence. Tumor dose-escalation sparing normal tissue using IMRT technology may improve the OS and in-field PFS.

Indexed as

Radiotherapy, ConformalRadiotherapy, Intensity-ModulatedHumansLymph NodesNeoplasm Recurrence, LocalRetrospective StudiesCancerintensity-modulated radiation therapylymph nodesoligometastasesoligo-recurrenceradiation therapy

Identifiers

PMID32871788
PMCPMC7652500

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.