Evidence map›Paper›PMID 32871778›Full record

ArticleIn vivo (Athens, Greece)

Do

Tomas Mickevicius, Alvita Vilkeviciute, Brigita Glebauskiene, Loresa Kriauciuniene, Rasa Liutkeviciene

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Biomedicines · 2022
    Article
  4. The Role ofCells · 2021
    Article
  5. Mediators of inflammation · 2021
    Article
  6. In vivo (Athens, Greece)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tomas MickeviciusMedical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania tomas.mickevicius94@outlook.com.
Alvita VilkeviciuteNeuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Brigita GlebauskieneNeuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Loresa KriauciunieneNeuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Rasa LiutkevicieneNeuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimTo evaluate the association between TRIB1(rs6987702) and IL-9(rs1859430, rs2069870) genotypes with the development and manifestation of pituitary adenoma (PA). MATERIALS AND

methodsThe study group included 141 patients with PA and the control group consisted of 287 healthy people. The genotyping of rs6987702, rs1859430 and rs2069870 was carried out using a real-time polymerase chain reaction.

resultsStatistically significant results were obtained regarding the rs1859430, but there were no significant results regarding rs6987702. We found that the rs1859430 A/A genotype increased the odds of having recurrent PA six times (p=0.006) under the co-dominant model and four times (p=0.021) under the recessive model. Furthermore, the analysis showed that the G/A genotype increased the odds of having recurrent PA 2.3 times (p=0.003) under the co-dominant model, while G/A and A/A genotypes increased the odds 2.7 times (p=0.011) under the over-dominant model.

conclusionCertain genotypes of rs1859430 can be associated with PA recurrence.

Indexed as

AdenomaPituitary NeoplasmsCase-Control StudiesGenetic Predisposition to DiseaseGenotypeHumansInterleukin-9Intracellular Signaling Peptides and ProteinsNeoplasm Recurrence, LocalPolymorphism, Single NucleotideProtein Serine-Threonine KinasesIL9 protein, humanInterleukin-9Intracellular Signaling Peptides and ProteinsProtein Serine-Threonine KinasesTRIB1 protein, humanIL-9 rs1859430Pituitary adenomarecurrencers2069870 gene polymorphismTRIB1 rs6987702 gene polymorphism

Identifiers

PMID32871778
PMCPMC7652474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.