Evidence map›Paper›PMID 32871770›Full record

ArticleIn vivo (Athens, Greece)

Expression of Ascorbate Peroxidase Derived from

Suzuro Hitomi, Shoichiro Kokabu, Ken-Ichiro Matsumoto, Yoshimi Shoji, Izumi Ujihara, Kentaro Ono

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Suzuro HitomiDivision of Physiology, Kyushu Dental University, Fukuoka, Japan hitomi.suzuro@nihon-u.ac.jp.
Shoichiro KokabuDivision of Molecular Signaling and Biochemistry, Kyushu Dental University, Kitakyushu, Fukuoka, Japan.
Ken-Ichiro MatsumotoQuantitative RedOx Sensing Group, Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Yoshimi ShojiQuantitative RedOx Sensing Group, Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Izumi UjiharaDivision of Physiology, Kyushu Dental University, Fukuoka, Japan.
Kentaro OnoDivision of Physiology, Kyushu Dental University, Fukuoka, Japan.
Kyushu Dental University · JPNational Institutes for Quantum and Radiological Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimAscorbate peroxidase (APX) derived from Cyanidioschyzon merolae, a primitive red alga living in high temperature and acidic environments, has greater anti-oxidative capacity than similar peroxidases occurring in other plants. In the present study, we examined whether expression of Cyanidioschyzon merolae-derived APX (cAPX) in mammalian cells increases cellular anti-oxidative capacity. MATERIALS AND

methodsThe cAPX gene was introduced into the mouse fibroblast-like cell line C3H10T1/2. Production of reactive oxygen species (ROS) and/or cell viability was assessed after heat, H

resultsHeat and H

conclusionIntroduction of cAPX increases the anti-oxidative capacity in mammalian cells.

Indexed as

Hydrogen PeroxideRhodophytaAnimalsAscorbate PeroxidasesCytosolGene Expression Regulation, PlantMiceAscorbate PeroxidasesHydrogen Peroxideanti-oxidative stressAscorbate peroxidaseCyanidioschyzon merolaefibroblastreactive oxygen species

Identifiers

PMID32871770
PMCPMC7652481
OpenAlexW3082214504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.