Evidence map›Paper›PMID 32871757›Full record

ArticleIn vivo (Athens, Greece)

Ablation Precision and Thermal Effects of a Picosecond Infrared Laser (PIRL) on Roots of Human Teeth: A Pilot Study

Reinhard E Friedrich, Maria Quade, Nate Jowett, Peter Kroetz, Michael Amling, Felix K Kohlrusch, Jozef Zustin, Martin Gosau, Hartmut SchlÜter, R J Dwayne Miller

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Infrared Laser Ablation and Capture of Biological Tissue.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  5. Making In Vitro Tumor Models Whole Again.Advanced healthcare materials · 2023
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Reinhard E Friedrich *Oral and Craniomaxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany rfriedrich@uke.de.
Maria Quade *Oral and Craniomaxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.
Nate JowettOtorhinolaryngology, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.
Peter KroetzAtomically Resolved Dynamics Division, Max Planck Research Department for Structural Dynamics, University of Hamburg, Hamburg, Germany.
Michael AmlingInstitute of Osteology and Biomechanics, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.
Felix K KohlruschOral and Craniomaxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.
Jozef ZustinInstitute of Osteology and Biomechanics, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.
Martin GosauOral and Craniomaxillofacial Surgery, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.
Hartmut SchlÜterInstitute of Clinical Chemistry and Laboratory Medicine, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.
R J Dwayne MillerAtomically Resolved Dynamics Division, Max Planck Research Department for Structural Dynamics, University of Hamburg, Hamburg, Germany.
Universität Hamburg · DEMax Planck Institute for the Structure and Dynamics of Matter · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimPicosecond infrared laser (PIRL) was investigated regarding its possible therapeutic application in cutting dental roots. MATERIALS AND

methodsExtracted human teeth were processed in the root area by laser ablations followed by histological evaluation. Dentin adjacent to the cutting surface was evaluated morphometrically.

resultsPIRL produced clearly defined cutting boundaries in dental roots. At the bottom of the cavity, the ablation surface became slightly concave. Heat development in this scantly hydrated tissue was considerable. We attributed the excess heating effects to heat accumulation due to multiple pulse overlap across a limited scan range imposed by tooth geometries.

conclusionDefined areas of the tooth root may be treated using the PIRL. For clinical translation, it would be necessary to improve beam delivery to facilitate beam steering for the intended oral application (e.g. by using a fiber) and identify optimal repetition rates/scan speeds combined with cooling techniques to minimize accumulated heat within ablation cavities.

Indexed as

LasersLaser TherapyHumansInfrared RaysPilot Projectsapicoectomylaser ablationoral surgeryPicosecond infrared laserthermal effects

Identifiers

PMID32871757
PMCPMC7652512
OpenAlexW3082701639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.