Evidence map›Paper›PMID 32871505›Full record

ArticleDrug and alcohol dependence2020

Social support modifies the association between hazardous drinking and depression symptoms among ART clients in Vietnam.

M X Nguyen, D Dowdy, C A Latkin, H E Hutton, G Chander, C Frangakis, K E Lancaster, T Sripaipan, Q X Bui, H V Tran and 1 more

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07514221 (Adaptation of Project Yes+ to Improve Mental Health and Reduce HIV-related Stigma Among Adolescent and Young Men Who Have Sex With Men Living With HIV in Vietnam), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.0field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07514221 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Adaptation of Project Yes+ to Improve Mental Health and Reduce HIV-related Stigma Among Adolescent and Young Men Who Have Sex With Men Living With HIV in Vietnam

TypeinterventionalSponsorHanoi Medical UniversityRan2026 to 2028Enrolled80ConditionsMental Disorder, HIV StigmaArmsTo-Hieu (I understand)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. The Protective Impact of Social Support on the Cascade Rates Between Internalizing Problems and Alcohol Misuse in Adolescence.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

M X NguyenDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Epidemiology, Institute of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam. Electronic address: binhminh@live.unc.edu.
D DowdyDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
C A LatkinDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
H E HuttonDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
G ChanderDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA.
C FrangakisDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
K E LancasterDepartment of Epidemiology, College of Public Health, Ohio State University, Columbus, OH, USA.
T SripaipanDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Q X BuiUNC Project Vietnam, Hanoi, Vietnam.
H V TranDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; UNC Project Vietnam, Hanoi, Vietnam.
V F GoDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Johns Hopkins University · USUniversity of North Carolina at Chapel Hill · USJohns Hopkins Medicine · USThe Ohio State University · US

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
The Effects of Drug Use, Depression, and Social Factors on HIV/HCV Care Continuum among PWID in Urban Areas: A Social-Network PerspectiveR01DA040488 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LATKIN, CARL A, TOBIN, KARIN E · 2015 to 2020
$4.0M
Reducing Hazardous Alcohol Use & HIV Viral Load:An RCT in ART Clinics in VietnamR01DA037440 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GO, VIVIAN F. · 2013 to 2017
$2.4M
NIAID NIH HHS P30 AI050410NIDA NIH HHS R01 DA037440NIDA NIH HHS R01 DA040488
6 · The paper itself

Abstract

introductionHazardous drinking is widespread among people with HIV (PWH). PWH are also vulnerable to depression due to HIV-related social stigma, and social support can play an important role in improving mental health for this population. No studies have explored whether social support modifies the association of hazardous drinking and depressive symptoms among PWH.

methodsWe used baseline data from a randomized controlled trial of two evidence-based alcohol reduction interventions among antiretroviral therapy clients in Vietnam. Hazardous alcohol use was defined as having a score ≥8 for men and ≥ 7 for women on the Alcohol Use Disorders Identification Test. The presence of depression symptoms was defined as a score ≥ 5 on the Patient Health Questionnaire-9. Social support was measured with a 5-question modified version of the Medical Outcomes Study Social Support Instrument. Crude (CPRs) and adjusted prevalence ratios (aPRs) of the association were presented.

resultsHazardous drinking was significantly associated with increased likelihood of having depressive symptoms (aPR = 1.26;95%CI 1.04-1.52). Hazardous drinking and depression symptoms were not associated among those with high social support (aPR = 1.01;95%CI 0.76-1.35), but were associated among those with medium (aPR = 1.24;95%CI 0.92-1.69) and low social support (aPR = 1.71;95%CI 1.25-2.34).

conclusionsSocial support significantly modified the association between hazardous drinking and depression symptoms among ART clients in Vietnam. Interventions to decrease hazardous alcohol use are broadly indicated for PWH in Vietnam and other low-resource settings, but special attention or modifications may be needed to support mental health among those with lower levels of social support.

Indexed as

Social SupportAdultAlcoholismAnti-Retroviral AgentsDepressionEthanolFemaleHIV InfectionsHumansMaleMiddle AgedPrevalenceSocial StigmaVietnamAnti-Retroviral AgentsEthanolDepressionEffect measure modificationHazardous alcohol usePeople living with HIVSocial supportVietnam

Identifiers

PMID32871505
PMCPMC8277424
OpenAlexW3080408809

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.