ArticleClinical imaging2020
Spontaneous subcutaneous emphysema and pneumomediastinum in non-intubated patients with COVID-19.
Article in Clinical imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 73 citations in OpenAlex.
- Thrombophilic Changes and Hematological Complications in Asthmatic Patients with COVID-19: A Systematic Review.Diseases (Basel, Switzerland) · 2025Review
- Spontaneous Pneumomediastinum in a Patient With Severe COVID-19 Pneumonia: A Case Report.Clinical case reports · 2025Article
- Mapping the vast landscape of multisystem complications of COVID-19: Bibliometric analysis.Heliyon · 2024Article
- Significant Spontaneous Pneumomediastinum and Extensive Subcutaneous Emphysema in a COVID-19 Patient.Reports (MDPI) · 2024Article
- Valsalva Manoeuvre-Induced Pneumothorax and Pneumomediastinum in a Covid-19 Patient with ARDS: An Unusual Mechanism for this Complication.European journal of case reports in internal medicine · 2024Article
- Severe SARS-CoV-2 Pneumonia and Pneumomediastinum/Pneumothorax: A Prospective Observational Study in an Intermediate Respiratory Care Unit.Journal of intensive care medicine · 2023Observational
- COVID-19 and spontaneous pneumothorax: a survival analysis.Journal of cardiothoracic surgery · 2023Article
- Case report: Severe pneumonia and pneumomediastinum in a previously robust adolescent caused by Omicron BA.5.2.Frontiers in medicine · 2023Article
- The use of lung ultrasound in COVID-19.ERJ open research · 2023Review
- Surgical management of pneumomediastinum in the COVID-19 patient.BMJ case reports · 2022Article
- Prognosis of Spontaneous Pneumothorax/Pneumomediastinum in Coronavirus Disease 2019: The CoBiF Score.Journal of clinical medicine · 2022Article
- Article
- Extracorporeal membrane oxygenation rescue for severe pneumocystis pneumonia with the Macklin effect: a case report.BMC infectious diseases · 2022Article
- Article
- Young convalescent COVID-19 pneumonia with extensive pneumomediastinum emphysema: Case report.Clinical case reports · 2022Article
- Spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema in non-ventilated COVID-19 patients.Future science OA · 2022Article
- A Case Series of Secondary Spontaneous Pneumomediastinum and Pneumothorax in Severe COVID-19 Pneumonia.Cureus · 2022Article
- A Dangerous Duo: Spontaneous Pneumomediastinum and Venous Thromboembolism at Presentation in a Patient with COVID-19 Pneumonia.Journal of community hospital internal medicine perspectives · 2022Article
- Imaging of COVID-19.Seminars in roentgenology · 2022Article
- The analysis of pleural complications of COVID-19 pneumoniaTurkish journal of medical sciences · 2021Article
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe describe the presenting characteristics and hospital course of 11 novel coronavirus (COVID-19) patients who developed spontaneous subcutaneous emphysema (SE) with or without pneumomediastinum (SPM) in the absence of prior mechanical ventilation. MATERIALS AND
methodsA total of 11 non-intubated COVID-19 patients (8 male and 3 female, median age 61 years) developed SE and SPM between March 15 and April 30, 2020 at a multi-center urban health system in New York City. Demographics (age, gender, smoking status, comorbid conditions, and body-mass index), clinical variables (temperature, oxygen saturation, and symptoms), and laboratory values (white blood cell count, C-reactive protein, D-dimer, and peak interleukin-6) were collected. Chest radiography (CXR) and computed tomography (CT) were analyzed for SE, SPM, and pneumothorax by a board-certified cardiothoracic-fellowship trained radiologist.
resultsEleven non-intubated patients developed SE, 36% (4/11) of whom had SE on their initial CXR. Concomitant SPM was apparent in 91% (10/11) of patients, and 45% (5/11) also developed pneumothorax. Patients developed SE on average 13.3 days (SD: 6.3) following symptom onset. No patients reported a history of smoking. The most common comorbidities included hypertension (6/11), diabetes mellitus (5/11), asthma (3/11), dyslipidemia (3/11), and renal disease (2/11). Four (36%) patients expired during hospitalization.
conclusionSE and SPM were observed in a cohort of 11 non-intubated COVID-19 patients without any known cause or history of invasive ventilation. Further investigation is required to elucidate the underlying mechanism in this patient population.
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