Evidence map›Paper›PMID 32870863›Full record

ArticleOptics letters2020

Characterizing chromatin packing scaling in whole nuclei using interferometric microscopy.

Aya Eid, Adam Eshein, Yue Li, Ranya Virk, David Van Derway, Di Zhang, Allen Taflove, Vadim Backman

Abstract read
In one paragraph

Article in Optics letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  3. Leveraging chromatin packing domains to target chemoevasion in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  10. Modeling properties of chromosome territories using polymer filaments in diverse confinement geometries.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2024
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  15. DNA density is a better indicator of a nuclear bleb than lamin B loss.bioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aya Eid
Adam Eshein
Yue Li
Ranya Virk
David Van Derway
Di Zhang
Allen Taflove
Vadim Backman

Funding

Translating buccal nanocytology for lung cancer screening into clinical practiceR01CA225002 · NCI · NORTHWESTERN UNIVERSITY · PI Vadim Backman, HARIHARAN SUBRAMANIAN · 2018 to 2026
$5.0M
Reducing Cancer Transcriptional Heterogeneity through Regulation of Chromatin StructureR01CA228272 · NCI · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM, ROY, HEMANT K. · 2018 to 2022
$3.2M
Risk-stratification of Prostate Cancers via Field Carcinogenesis NanocytologyR01CA200064 · NCI · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM, CRAWFORD, SUSAN E. · 2015 to 2019
$3.1M
NCI NIH HHS R01 CA200064NCI NIH HHS R01 CA225002NCI NIH HHS R01 CA228272
6 · The paper itself

Abstract

Chromatin is the macromolecular assembly containing the cell's genetic information, and its architectural conformation facilitates accessibility to activation sites and thus gene expression. We have developed an analytical framework to quantify chromatin structure with spectral microscopy. Chromatin structure can be described as a mass fractal, with packing scaling

Indexed as

ChromatinHumansInterferometryLightMicroscopyChromatin

Identifiers

PMID32870863
PMCPMC7951997

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.