ArticleInternational journal of clinical practice2021
Clinical trials: Predictors of knowledge and attitudes towards participation.
Article in International journal of clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Clinical Trial Perceptions Among Patients Enrolled in a Precision Oncology Protocol at an Appalachian-Serving Cancer Center.Psycho-oncology · 2026Article
- Optimization of patient and site engagement in the SYNCHRONIZE™ phase 3 clinical trial program for survodutide in obesity through clinical trial simulation.Contemporary clinical trials communications · 2026Article
- Qualitative evaluation to improve participant engagement and retention in remote COVID-19 treatment trials.Discover public health · 2025Article
- Use of complementary and alternative medicine among females with polycystic ovary syndrome in Jordan: a cross-sectional study.BMJ open · 2024Article
- Is there a relationship between attitudes of general practitioners/family doctors and attitudes of their patients regarding industry-sponsored clinical investigations? A cross-sectional survey in a convenience sample of doctors and patients across nine European countries.Croatian medical journal · 2024Article
- Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourth-Year PharmD Undergraduates from Riyadh, Saudi Arabia.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Factors influencing willingness to participate in ophthalmic clinical trials and strategies for effective recruitment.International journal of ophthalmology · 2024Article
- Article
- Factors related to eczema clinical trial participation among adult patients and caregivers.Contemporary clinical trials communications · 2023Article
- Article
- Knowledge and Attitude towards Clinical Trials among General Population of Northern Saudi Arabia during COVID-19 Era: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2023Article
- Knowledge and attitudes towards clinical trials among women with ovarian cancer: results of the ACTO study.Journal of ovarian research · 2022Observational
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
aimsClinical trials (CTs) are critical to advancing of patient care. Understanding the public's knowledge and the attitudes towards participating in CTs is important for their successful implication. In Jordan this data are currently not available. The present study aimed to explore the knowledge, attitude and perception of Jordanians towards CTs participation.
methodsA cross-sectional study was conducted on 1216 Jordanians recruited from public hospitals and pharmaceutical research centres.
resultsAbout 20.5% of the respondents have previously participated in a CT. About 68.3% and 50.1% had good knowledge and positive attitude towards CTs, respectively. Good knowledge was associated with male gender (OR = 1.696, 95% CI = 1.284-0.240, P < .001), higher education (OR = 1.433, 95% CI = 1.107-1.856, P = .006) and healthy condition (OR = 1.822, 95% CI = 1.234-2.690, P = .003); while older age was associated with a poor knowledge (OR = 0.985, 95% CI = 0.972-0.998, P = .026). Female gender (OR = 1.817, 95% CI = 1.406-2.349, P < .001), higher education (OR = 1.294, 95% CI = 1.017-1.646, P = .036) and previous participation (OR = 1.919, 95% CI = 1.388-2.653, P < .001) were factors predicting the positive attitudes. A very weak positive correlation was found between knowledge and attitude (Spearman's r = 0.074, P = .01). Regarding perceptions, most of the respondents (85.3%) perceive that CTs are conducted in an ethical manner in Jordan, only 52.9% however feel comfortable towards participation. A moderate positive correlation was found between knowledge and perception (Spearman's r = 0.275, P < .001). Taking part in a CT significantly affect knowledge, attitudes and perceptions.
conclusionsThis study revealed important insights regarding knowledge, attitudes and perception of Jordanians towards CTs. Educational interventions can improve awareness of the ethical standards under which CTs are conducted affecting the perception to participate. Promotion of CTs among patients and healthy individuals is needed to increase participation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.