Evidence map›Paper›PMID 32870397›Full record

ArticleMikrochimica acta2020

A signal-on electrochemical aptasensor based on silanized cellulose nanofibers for rapid point-of-use detection of ochratoxin A.

Ahmed Y El-Moghazy, Noha Amaly, Georges Istamboulie, Nitin Nitin, Gang Sun

Open access · greenAbstract read
In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
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  7. Electrospun Nanofibers for Sensing and Biosensing Applications-A Review.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Ahmed Y El-MoghazyDepartment of Biological and Agricultural Engineering, University of California, Davis, Davis, CA, 95616, USA. aelmoghazy@ucdavis.edu.ORCID http://orcid.org/0000-0002-5743-7305
Noha AmalyDepartment of Biological and Agricultural Engineering, University of California, Davis, Davis, CA, 95616, USA.
Georges IstamboulieBiocapteurs-Analyses-Environnement, University of Perpignan Via Domitia, 66860, Perpignan, France.
Nitin NitinDepartment of Biological and Agricultural Engineering, University of California, Davis, Davis, CA, 95616, USA.
Gang SunDepartment of Biological and Agricultural Engineering, University of California, Davis, Davis, CA, 95616, USA. gysun@ucdavis.edu.
City of Scientific Research and Technological Applications · EGUniversity of California, Davis · USUniversité de Perpignan · FR

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI HAMMOCK, BRUCE D · 1987 to 2021
$50.1M
National Institute of Environmental Health Sciences (NIEHS) 5P42ES004699NIEHS NIH HHS P42 ES004699USDA National Institute of Food and Agriculture (USDA-NIFA) 2015-68003-23411
6 · The paper itself

Abstract

An innovative ultrasensitive electrochemical aptamer-based sensor was developed for ochratoxin A (OTA) detection in cold brew coffee through revolutionary combination of nanofibers, electrochemical method, and aptamer technologies. The assembly of the aptasensor was based on the activation of silanized cellulose nanofibrous membranes as a supporting matrix for methylene blue (MB) redox probe-labeled aptamer tethering. Cellulose nanofibrous membranes were regenerated by deacetylating electrospun cellulose acetate nanofibrous membranes with deacetylation efficacy of 97%, followed by silanization of the nanofiber surfaces by using (3-aminopropyl)triethoxysilane (APTES). A replacement of conventionally casted membranes by the nanofibrous membranes increased the active surface area on the working electrode of a screen-printed three-electrode sensor by more than two times, consequently enhancing the fabricated aptasensor performance. The developed aptasensor demonstrated high sensitivity and specificity toward OTA in a range 0.002-2 ng mL

Indexed as

Aptamers, NucleotideBiosensing TechniquesCelluloseCoffeeElectrochemical TechniquesFood ContaminationImmobilized Nucleic AcidsLimit of DetectionMethylene BlueNanofibersOchratoxinsOxidation-ReductionPropylaminesSilanesamino-propyl-triethoxysilaneAptamers, NucleotideCelluloseCoffeeImmobilized Nucleic AcidsMethylene Blueochratoxin AOchratoxinsPropylaminesSilanesAptamerCellulose nanofibersCoffee analysisElectrochemical aptasensorOchratoxin APoint-of-use

Identifiers

PMID32870397
PMCPMC7780854
OpenAlexW3082698764

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.