Evidence map›Paper›PMID 32870161›Full record

ArticleJMIR mental health2020

Utilizing Machine Learning on Internet Search Activity to Support the Diagnostic Process and Relapse Detection in Young Individuals With Early Psychosis: Feasibility Study.

Michael Leo Birnbaum, Prathamesh Param Kulkarni, Anna Van Meter, Victor Chen, Asra F Rizvi, Elizabeth Arenare, Munmun De Choudhury, John M Kane

Abstract read
In one paragraph

Article in JMIR mental health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  11. A prognostic model for predicting functional impairment in youth mental health services.European psychiatry : the journal of the Association of European Psychiatrists · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael Leo Birnbaum *The Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, United States.ORCID https://orcid.org/0000-0002-4285-7868
Prathamesh Param Kulkarni *Cornell Tech, Cornell University, New York City, NY, United States.ORCID https://orcid.org/0000-0002-8555-2298
Anna Van MeterThe Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, United States.ORCID https://orcid.org/0000-0003-0012-206X
Victor ChenGeorgia Institute of Technology, Atlanta, GA, United States.ORCID https://orcid.org/0000-0001-9378-8615
Asra F RizviThe Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, United States.ORCID https://orcid.org/0000-0001-8552-330X
Elizabeth ArenareThe Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, United States.ORCID https://orcid.org/0000-0003-0911-3207
Munmun De ChoudhuryGeorgia Institute of Technology, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-8939-264X
John M KaneThe Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, United States.ORCID https://orcid.org/0000-0002-2628-9442

Funding

Leveraging Social Media Data and Machine Learning to Optimize Treatment Paradigms for Youth with SchizophreniaR01MH117172 · NIMH · GEORGIA INSTITUTE OF TECHNOLOGY · PI DE CHOUDHURY, MUNMUN · 2019 to 2022
$2.6M
Social Media Signals for Post-traumatic Stress and Anxiety in Crisis-Inflicted CommunitiesR01GM112697 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI DE CHOUDHURY, MUNMUN · 2014 to 2018
$1.4M
The Digital Phenotype of Bipolar Disorder: Harnessing Technology to Identify Bipolar Mood Symptoms - Revision - 1K23MH120505 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI VAN METER, ANNA ROBINSON · 2019 to 2024
$1.0M
NIGMS NIH HHS R01 GM112697NIMH NIH HHS K23 MH120505NIMH NIH HHS R01 MH117172
6 · The paper itself

Abstract

backgroundPsychiatry is nearly entirely reliant on patient self-reporting, and there are few objective and reliable tests or sources of collateral information available to help diagnostic and assessment procedures. Technology offers opportunities to collect objective digital data to complement patient experience and facilitate more informed treatment decisions.

objectiveWe aimed to develop computational algorithms based on internet search activity designed to support diagnostic procedures and relapse identification in individuals with schizophrenia spectrum disorders.

methodsWe extracted 32,733 time-stamped search queries across 42 participants with schizophrenia spectrum disorders and 74 healthy volunteers between the ages of 15 and 35 (mean 24.4 years, 44.0% male), and built machine-learning diagnostic and relapse classifiers utilizing the timing, frequency, and content of online search activity.

resultsClassifiers predicted a diagnosis of schizophrenia spectrum disorders with an area under the curve value of 0.74 and predicted a psychotic relapse in individuals with schizophrenia spectrum disorders with an area under the curve of 0.71. Compared with healthy participants, those with schizophrenia spectrum disorders made fewer searches and their searches consisted of fewer words. Prior to a relapse hospitalization, participants with schizophrenia spectrum disorders were more likely to use words related to hearing, perception, and anger, and were less likely to use words related to health.

conclusionsOnline search activity holds promise for gathering objective and easily accessed indicators of psychiatric symptoms. Utilizing search activity as collateral behavioral health information would represent a major advancement in efforts to capitalize on objective digital data to improve mental health monitoring.

Indexed as

diagnostic predictiondigital biomarkersdigital datadigital phenotypingGoogleinternet search activitymachine learningrelapse predictionschizophrenia spectrum disorders

Identifiers

PMID32870161
PMCPMC7492982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.