SynthesisJournal of clinical laboratory analysis2020
The impact of pre-analytical variations on biochemical analytes stability: A systematic review.
Synthesis in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of pre-analytical variations on biochemical analytes stability: A systematic review.Journal of clinical laboratory analysis · 2020Pooled it
- Assessment of Biochemical Analytes Stability: The Role of Centrifugation and Storage Conditions in the Preanalytical Phase.Analytical science advances · 2026Article
- Navigating preanalytical challenges: a real-world study on single-tube pneumatic tube systems.Frontiers in physiology · 2026Article
- Assessment of the stability of 20 biochemical analytes in serum and whole blood samples after storage at nonstandard temperatures.Practical laboratory medicine · 2026Article
- Post-exercise creatine kinase variability: a literature review.Biochemia medica · 2025Review
- The Impact of Delayed Processing of Chilled Whole Blood Specimens on the Measurement of Nutritional Biomarkers in the United Kingdom National Diet and Nutrition Survey Rolling Programme.The Journal of nutrition · 2024Article
- The Stability of the Anti-Müllerian Hormone in Serum and Plasma Samples under Various Preanalytical Conditions.Diagnostics (Basel, Switzerland) · 2023Article
- Optimized protocol for quantification of extracellular nicotinamide adenine dinucleotide: evaluating clinical parameters and pre-analytical factors for translational research.Frontiers in medicine · 2023Article
- Impact of Time Delay in the Analysis of Serum Ionized Calcium, Sodium, and Potassium.Journal of laboratory physicians · 2022Article
- Serum Analytes of American Mink (Neovison Vison) Challenged with Aleutian Mink Disease Virus.Animals : an open access journal from MDPI · 2022Article
- Assessing the influence of true hemolysis occurring in patient samples on emergency clinical biochemistry tests results using the VITROSBiomedical reports · 2021Article
- Biospecimen Digital Twins: Moving from a "High Quality" to a "Fit-for-Purpose" Concept in the Era of Omics Sciences.Cancer genomics & proteomicsReview
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveA common problem in clinical laboratories is maintaining the stability of analytes during pre-analytical processes. The aim of this study was to systematically summarize the results of a set of studies about the biochemical analytes stability.
methodsA literature search was performed on the Advanced search field of PubMed using the keywords: "(stability) AND (analytes OR laboratory analytes OR laboratory tests OR biochemical analytes OR biochemical tests OR biochemical laboratory tests)." A total of 56 entries were obtained. After applying the selection criteria, 20 articles were included in the study.
resultsIn the 20 included references, up to 123 different analytes were assessed. The 34 analytes in order of the most frequently studied analytes were evaluated: Alanine aminotransferase, aspartate aminotransferase, potassium, triglyceride, alkaline phosphatase, creatinine, total cholesterol, albumin, lactate dehydrogenase, sodium, calcium, γ-glutamyltransferase, total bilirubin, urea, creatine kinase, inorganic phosphate, total protein, uric acid, amylase, chloride, high-density lipoprotein, magnesium, glucose, C-reactive protein, bicarbonate, ferritin, iron, lipase, transferrin, cobalamin, cortisol, folate, free thyroxine, and thyroid-stimulating hormone. Stable test results could be varied between 2 hours and 1 week according to the type of samples and/or type of blood collection tubes on a basic classification set as refrigerated or room temperature.
conclusionsBiochemical analytes stability could be improved if the best pre-analytical approaches are used.
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