Evidence map›Paper›PMID 32869566›Full record

ArticleInvestigative and clinical urology2020

Novel insight into pressurization of the male and female urethra through application of a multi-channel fibre-optic pressure transducer: Proof of concept and validation.

Ryan E Stafford, John Arkwright, Phil G Dinning, Wolbert van den Hoorn, Paul W Hodges

Open access · diamondAbstract readValidation Study
In one paragraph

Article in Investigative and clinical urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ryan E StaffordSchool of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia.ORCID 0000-0002-5444-477X
John ArkwrightCollege of Science and Engineering, Flinders University, Adelaide, Australia.ORCID 0000-0001-6460-6499
Phil G DinningDepartment of Gastroenterology and Surgery, Flinders Medical Centre, Adelaide, Australia.ORCID 0000-0001-8910-2801
Wolbert van den HoornSchool of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia.ORCID 0000-0002-9658-2388
Paul W HodgesSchool of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia. p.hodges@uq.edu.au.ORCID 0000-0002-1206-9107
The University of Queensland · AUFlinders Medical Centre · AUFlinders University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo confirm feasibility of recording pressure along the length of the urethra using a multi-sensor fibre-optic pressure catheter; to identify the spatial and temporal features of changes in pressure along the urethra at sites related to specific striated pelvic floor muscles; and to investigate the relationship between urethral pressures and activation of individual pelvic floor muscles estimated from ultrasound imaging. MATERIALS AND

methodsProof-of-concept study including one male (47 years old) and one female (33 years old). A multi-sensor fibre optic pressure catheter (10 mm sensor separation) was inserted into the urethra. Pressure data were recorded simultaneously with trans-perineal ultrasound imaging measures of pelvic floor muscle activity during sub-maximal and maximal voluntary contractions and evoked coughs.

resultsPressure changes along the urethra were recorded in all tasks in both participants. Face validity of interpretation of pressure measures with respect to individual muscles was supported by correlation with ultrasound-measured displacements induced by the relevant muscles. Onset of pressure increase occurred in a distal to proximal sequence in the urethra of the male but not the female during voluntary contraction. Peak urethral pressures varied in location, timing and amplitude between tasks. Evoked cough induced in the greatest urethral pressure increase across all tasks for both participants.

conclusionsThe high spatial resolution pressure catheter provide viable and valid recordings of urethral pressure in a male and female. Data provide preliminary evidence of sex differences in spatial and temporal distribution of urethral pressure changes.

Indexed as

AdultFeasibility StudiesFemaleFiber Optic TechnologyHumansMaleMiddle AgedMuscle ContractionPelvic FloorPressureProof of Concept StudyTransducers, PressureUltrasonographyUrethraCathetersPelvic floorPressureReproductive and urinary physiological phenomena

Identifiers

PMID32869566
PMCPMC7458876
OpenAlexW3034721384

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.