Evidence map›Paper›PMID 32869563›Full record

SynthesisInvestigative and clinical urology2020

Effectiveness and safety of partial nephrectomy-no ischemia vs. warm ischemia: Systematic review and meta-analysis.

Sergio Hernando Mina-Riascos, Gonzalo Vitagliano, Herney Andrés García-Perdomo

Open access · diamondAbstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Investigative and clinical urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Sergio Hernando Mina-RiascosDepartment of Surgery, Urology Division, UROGIV Research Group, Universidad del Valle, Cali, Colombia.ORCID 0000-0002-7321-9754
Gonzalo VitaglianoOncology and Urolaparoscopy Unit, Urology Service, Hospital Alemán de Buenos Aires, Buenos Aires, Argentina.ORCID 0000-0003-1150-6739
Herney Andrés García-PerdomoDepartment of Surgery, Urology Division, UROGIV Research Group, Universidad del Valle, Cali, Colombia. Herney.garcia@correounivalle.edu.co.ORCID 0000-0001-6945-8261
Universidad del Valle · COHospital Alemán · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to determine the effectiveness and safety of partial nephrectomy (PN) without ischemia compared with PN with warm ischemia for reducing the deterioration in renal function in patients with cT1 renal tumors. MATERIALS AND

methodsWe conducted a systematic review that included patients over 18 years of age who underwent PN with or without warm ischemia for cT1 renal tumors. The primary outcome was impaired renal function. A search strategy was performed in MEDLINE, EMBASE, LILACS, CENTRAL, the article reference lists, and the unpublished literature to reach saturation of the information. We assessed the risk of bias with the methodological index for nonrandomized studies (MINORS) tool, and we performed a meta-analysis according to the type of variable.

resultsWe found a total of 5,682 articles, of which 14 met the inclusion criteria. Seven studies evaluated renal function, identifying a difference in means (MD) of 3.50 (95% confidence interval [CI], 1.16 to 5.83), favoring no ischemia. We did not find any significant differences regarding intraoperative bleeding or operative time (MD, 55 mL; 95% CI, -33.16 to 144.08; and MD, 1.87; 95% CI, -20.47 to 24.21; respectively).

conclusionsIn this study, PN without ischemia showed a decrease in deterioration of the estimated glomerular filtration rate compared with warm ischemia.

Indexed as

Warm IschemiaHumansKidney NeoplasmsNeoplasm StagingNephrectomyTreatment OutcomeCold ischemiaMeta-analysisNephrectomySystematic reviewWarm ischemia

Identifiers

PMID32869563
PMCPMC7458877
OpenAlexW3034519161

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.